Hi, I am sitting here panicking and worrying. Along with 20mg injection weekly of MTX, 10mg daily pred, 4 types of BP meds, omeprazole, 6 days of folic acid, co-codomal I also take 90mg daily of arcoxia (enterocoxib or something to give it its proper name!). My eGfR (kidney function) is down to 32 and should be over 100. I know the GP will take me off arcoxia (my anti-inflamm) as it is causing the kidney problem. Anybody else have this situation? If I try without an anti-inflam I increase swelling, stiffness and pain. Also feel generally rubbish. I have another blood test/urine test tomorrow to double check readings, but I know they are correct as they have been steadily decreasing weekly and I have already been taken off arcoxia once. Is there an alternative to NSAIDs that others use? I have to be very careful as the BP med ramipril very kindly gave me angio-oedema which means my drug usage is quite restricted anyway. Winter is coming and cold weather really does not agree with my fingers, especially, so am dreading being without a daily anti-inflamm. Thank you very much.