i have had ra for two and half years, i test negative to the rheumatoid factor, although doc says i do have ra.. iam on methetrexate, and tnf humaira, it hasnt helped alot, my knees sweel up about every 8 weeks, needing to get them aspirated, and steriod injected into. With not being able to have a steriod everytime i get them drained, r nurse says its not worth draining the knee, so i have to suffer pain and not being able to get around properly, until the time comes to have another stereiod. Doc did mention one time i might need the knee looked at the orthepdcs. i think there is some kind of damage in the knee, which is causing the swelling in the knee, Has anyone had this happen to them, if so what have you done?? sometimes when i ring the rheumt helpline the nurses arnt that helpfull, and say i have to go to my gp, and get refered.