metratrexate and abnormal bloods!: hi all! As some of... - NRAS

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metratrexate and abnormal bloods!

Mybirthday1975 profile image
10 Replies

hi all!

As some of you have already seen I’ve had some abnormal bloods and liver results for the first time and I’m having bloods reported in 4 wks but my question is tonight is my injection night for methotrexate and I’ve still injected it as I really need it having a massive flur up!!

My question is do any of you guys still inject even though your bloods are a little bit out of range?

Thanks all replies appreciated 👍

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Mybirthday1975 profile image
Mybirthday1975
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10 Replies
Madmusiclover profile image
Madmusiclover

yes!

Runrig01 profile image
Runrig01

Your rheumatology team would have contacted you with instructions to hold the MTX, if they were concerned. Was it rheumatology who requested retest in 4 weeks?

The one tme I had raised liver function enzymes, was when I’d been on Azathioprine and they’d increased my dose. I had to stop till I had an ultrasound of my liver. Thankfully it had recovered, I was switched to MTX. This was 8yr ago, and I’ve had no further issues

Gilliancheche profile image
Gilliancheche

Are your rheumatology dept aware of the blood test results? If they are they would have told you to stop medication if that was needed. If not you should contact them and discuss asap.

Oppenheimer123 profile image
Oppenheimer123

I had abnormal ALT and GP just said retest in 6 weeks. Rheumatology advice line when contacted were concerned about this and wanted to retest sooner. Also had to stop taking ibuprofen which brought it right down even though continued with MTX. I suppose my answer would be make sure you contact Rheumatology if possible.

bpeal1 profile image
bpeal1

You would have been informed to stop medication when you were contacted about the blood test results if it was necessary.

stbernhard profile image
stbernhard

Yes indeed 👍. But of course this is your decision. If you worry a lot about it, then please contact your rheumatology team and discuss it with them before injecting. It never mattered to me if I was a day out with the MTX now and then.

aliplayspiano profile image
aliplayspiano

if the bloods were done by rheumatology and they hadn’t told me to hold the meds then yes I would take them. There have been times when they have told me to hold off the meds until they have retested and other times when they’ve asked me to retest in a month but told me to carry on with the meds.

smilelines profile image
smilelines

I have taken my medicine with liver enzymes higher than normal.

Wobbies profile image
Wobbies

Yes I carry on unless advised not to.

Chockyuk profile image
Chockyuk

Hi - for the past six months out of nowhere mine are up too, ALT was in the 90’s at one point. I just speak to the nurse for guidance. I was told to come off it completely for 3 weeks, results went normal, now on a lower dose, they are a bit raised but not as bad as they were.

So I would be guided by them really if you can get in touch. My GP went into overdrive and sent me for a pointless liver scan, even though I knew it was the MTHX.

For me, I was on 20mg and I’m also on Sulphasalazine. I’ve reduced to 15mg on advice from the nurse, but I have been feeling some familiar aches - who would have guessed such a small reduction could make such a difference. 🤷‍♀️

They did tell me though not to stop or reduce unless you advised to by your Rheumatologist or nurse.

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