Anyone else using Jyseleca

[Minnie83]

About 7 weeks ago i was taken off Sulfasalazine, Methotrexate & imraldi injection and moved onto Jyseleca. It now feels like all the aches & pains i had before i started on sulfasalazine are back with new pains in different joints! it feels like i’m on a placebo as i’m not getting an pain relief !! at the moment i’m taking so much paracetamol and Ibuprofen i rattle!!! anyone with experience on jyseleca positive or negative would be helpful to hear thanks Minnie 😊

[Pastels]

Hi,

I’ve been taking Filgotinib 200mg for 18months 2years now and it’s been the best drug for controlling my RA. I did have one horrible flare post covid about 10 months ago but my RA has now settled again. I do find if I stop for any reason other illness or surgery my RA flares within I to 2 weeks.

I think I’ve responded well to Filgotinib and quite quickly too within a couple of weeks. I guess everyone is different in their responses to drugs if you can perhaps chat to your rheumatology nurse. I know that several folk on this site take Filgotinib plus other RA meds.

When my RA is controlled I take no analgesic.

Wishing you the very best sorting your medication out.

[nanapat61]

Hi Minnie83 - I've no experience of Jyseleca but just wanted to say I'm sorry you're feeling so rough and hope things improve for you soon. Could you perhaps get in touch with your Rheumatology Nurse/s via their Advice Line and see what they can advise?

[KittyJ]

until your new med starts to work you can of course start to get a return of symptoms, hopefully it’ll start to work soon but do speak to your GP about pain relief in the meantime if you need to. 🤞🏻

[Chocnbags]

yes I have been taking Filigotnib for 2 years in combination with Methotrexate.it really has improved my life and no side effects whatsoever

[Bella59]

I have been on Filgotinib for about 14 months in combo with Metojet pen 15mg.So far i would say this has been the most helpful Jak Inhibator.I tried three Dmards,them several biological injections.Wait a few months to see if it kicks in.I hope this one will help you.Good Luck.

[Amnesiac3637]

Hi Minnie83. Have been on Filgotinib (Jyseleca) 100 mgs (due to age,71) since April after Tocilizumab failed me.

It’s been fairly effective though I still have swollen joints and some pain which is annoying and I’m still taking Paracetamol and Ibuprofen though not consistently or nearly as often as when I started on it. I think you’ll probably have to give it a bit longer to work as sometimes, as you know, these drugs take a bit of time to get going for different people.

Hope it starts to work for you as these JAKs are targeted and very effective when they do work. I haven’t had any side effects from it and as it’s in tablet form it’s easy to stop if you run into trouble. This is my second - was on Baricitinib for three years and it was really effective but it stopped working after covid so there are others you can try if one doesn’t suit you.

All best and hope this is the one for you!

[cozzycoz]

hi Minnie, I’m currently waiting to se my Rheumatologist after being on Filgotinib since March, I have same as you , my hands are so stiff and sore and that’s with Methotrexate also, think I need something else, I did well on Rituxuimab not sure why they took me off it!! Probably down to cost I suspect ?! Contact your rheumatologist they can check and change things if not working for you! Hopefully get mine sorted today ! X

[BikerEssex]

Am no expert on sulfasalazine. I know when i got put on it the doctor said will could take upto 6 weeks for it to start working. been taking for almost 4 months now i have good and bad days more good then dad am happy to say. As to the other medication sorry i can't help the only advise is when you next see your rheumatology nurse explain it to them they might decide to up your meds.

Hope it gets sorted all the best,

[Babaj12345]

Hi im on sulfasalazine have been for over 3 years no side effects but they have coupled mine with an injection Kevzara which i do myself every 2 weeks I have found the injection to be a god send

[Sarmita50]

Have not heard of this.Are you okay with these injections ?