Baracitinib - morning or night?

[Inanotherlife]

Hello everyone,

Any experiences with getting a better result when taking at night?

I’ve been on & off Baracitinib due to surgery and infections but have always taken in the morning which sees my RA at its worst in terms of pain. I usually ‘get going’ around midday!

I wondered if I should gradually shift the time to bedtime with the idea that it might be more effective in helping the mornings if that make sense? Appreciate any thoughts 😊

Also, I have a telephone pip assessment coming up due to a Change of circumstances for I submitted due to the condition worsening. I’ll be a nervous wreck until it’s over but can I ask if anyone has experience in terms of how to approach it, other than to obviously explain how RA affects you?

[Madmusiclover]

I’ve always taken mine at night. I’m not sure it makes much difference. Does the patient leaflet advise?

[Inanotherlife in reply to Madmusiclover]

Thank you, I going to give it a try but will have to delay it gradually each day because I know I need it each morning. Info says, take anytime, with or without food..

[Amnesiac3637]

It honestly makes no difference when you take it. It’s not a pain killer as such so you can take it when you want. When I was on it I took the first tablet at night in case of side effects which I reckoned would be easier if I slept through. Didn’t have any as it happened but took it at night anyway as it was easier to remember. Am now on Filgotinib which is similar and have done the same thing. Once these JAks are in your bloodstream and working to target they’ll do it whatever.

Can’t help with PIP query though as I am not doing so well now I think I may have a go at applying. Please let us know how you get on with both of your queries. Best of luck.

[Inanotherlife]

Thank you, yes I’m going to try it at night.

Pip - thanks and will do. It’s an arduous task but I’m hoping I’m successful.

[Deeb1764]

take mine in morning as it’s a 24hr as such so I think you can take it anytime.

Re PIp just be honest about your condition and how it affects you what has got worse and what you struggle with. They have their questions so just think before you reply so you don’t forget to say anything and take a deep breath before you answer the call 🥰

[Inanotherlife in reply to Deeb1764]

Thanks 😊

Pip - I’m never sure if I’ve said enough or too much with these assessments, so stressful!

[Mmrr]

I've taken all 4 JAKs that I have been on the in the morning, but i don't think it makes much difference.I also take leflunomide, take that in the evening.

[Inanotherlife in reply to Mmrr]

Thanks for reply. Can I ask if any of those 4 Jaks was better than another and did each one stop working over time?

[Deeb1764 in reply to Inanotherlife]

Unfortunately it’s a one drug does not fit all. We all respond differently on how our RA affects us and how we react to meds. It took me 5 drugs before I was on Baritcitnib and so far so good. So for some if they have come off a med due to an issue with RA when they go back on it does not work as well but then others have been on one drug for long periods of time.

[Mmrr in reply to Inanotherlife]

I've found the JAKs to be useful in equal measure, for me much better than biologics. They all stopped working over time. (I've been on 3 JAKs not 4, fat finger day 🙄).

[Joannos]

I take mine in the morning, only if I forget later in the day, haven't noticed any difference as to when I take it. Choose a time which fits your routine. Especially as there are no 'specific' instructions Hope this helps.

[zen4]

Its a build up drug so the timing makes no difference at all. Take it when you will always remember it..

In relation to PIP I haven't completed that form so I am not totally sure but I have completed DLA [ its forerunner] a long time ago. I think the main thing is to need help/support daily or if you need equipment or if you have to do things in different ways or it take you ages or you cannot do it at all then make sure you write it all down. State the obvious.! They won't know if you do not explain it. Also they like all the medical proof Do not underestimate your problems. Compare yourself with what you would be able to do if you didn't have RA. Completing the form will feel a very negative experience but it will be worth it for the extra money which you need to live your life the best way you can. Hope this helps a bit

[zen4]

I forgot to say if you have fatigue remember to include that as well!

[Inanotherlife in reply to zen4]

Thank you, I need to jot some things down so I remember. I currently get standard rate for Daily living activities(?) but I’ve got worse with mobility and desperately need (not really want!) a blue badge because when I feel I can go shopping, I’m struggling with the extra walk to & from the car. I did apply for a badge but was turned down.

[Green230461]

I was told to take statins at night and baricitinib in the morning for breakfast. No ideas why but it works for me 🏖️