Jyseleca

[Lilahloo]

I Have been on the new drug Jyselica - filgotinib 100gm for 6 months now going into flare up. Unable to take higher dose due to age so GP given me steriods until I see Consultant. Has anybody else been on this new drug and suffered a flare up.

[sylvi]

Sorry i can't help you. I hope you get some answers soon. xxxx

[Mmrr]

I've been on 200mgs Filgotinib per day for around 1 year, it gives me some benefits. It is worth taking, but my ankles and wrists are still swollen and tender. I also take Leflunomide and prednisolone. But I've always had to take some prednisolone with every medication that I've taken.

[Chocnbags]

Yes I have been taking it for 18 months have no problems most of the time but have had 2 bad knee flares which lasted 24 hrs at the most .it' has really helpes me li e a normal live again .

[Lilahloo in reply to Chocnbags]

Thank you for replying are you on 200 or 100 mg x

[Chocnbags in reply to Lilahloo]

I take 200mg daily

[Lilahloo in reply to Chocnbags]

Thank you that seems to work but due to age I can only have 100gm daily. Apparently something to do with kidneys over certain age. I am now taking steriods with them and getting back to normal. Thank you for your help.

[Doodlereggie]

I too have been on filgotinib for 6 months and it is marvellous.crp reduced from 78 to 7 ,no pain and no side effects that I know of and no flares.However rheumy is going to reduce from 200mg to 100 mg with my agreement as I am 78 and the higher dose is not recommended as you say.I also take prednisolone and have done for over 20 years,when 5 mg has been my holding dose.Because of success of filgotinib reducing steroids gradually and now on 4 mg for a month,and may stick at that because of lowering dose of JAK.Will have to see how it goes,and be guided by my rheumy as I trust him implicitly.Am having kidney ultrasound on Friday,as too much calcium,with a view to having parathyroidectomy but as appointment with endicronologist is not until July 2024 they don’t seem too worried.So,bit all up in the air at the moment,but feel so good after all these years,able to walk again,and use my hands,that I have decided to take each day as a bonus.Other people on this forum have reduced from 200 mg to 100mg,with no reduction in results,so taking comfort in that.Good luck with meds and Hope steroids give you a boost.xx

[Wedgwood123]

I’m on the same drug and have had a few flare ups but not nearly so bad as before taking the new drug