I’ve been on MTX for 5 months, started on a Saturday but would like to switch to taking it on Wednesday. Any advice? Thanks!

[Wolfegang]

Changing MTX day

[Boxerlady]

I think that the usual method is to take it one day later each week e.g. Sunday, Monday, Tuesday, Wednesday. If your RA is well-controlled, I suppose that you could just miss a dose and go to the following Wednesday i.e. leave 10 days between doses. The general rule is that you mustn't leave less than a week between doses.

[Wolfegang in reply to Boxerlady]

Thanks for replying, I think I’ll just skip my dose this Saturday and take it on Wednesday

[nomoreheels]

I take MTX on a Wednesday too, but I always have. As you want to change by several days it would be too close to your next dose to just start taking it next Wednesday. That being the case the best way to do it is to move on a day each week, so you could take it Sunday this week, Monday next week etc until you get to Wednesday. Or, you could miss taking it this Saturday & take your next dose on Wednesday, as long as you don't take it more than once in a week you should be ok. On the odd occasion I’ve not taken it for a week, sometimes 2 & felt fine, but by three weeks (not by choice) I really miss it, though I’ve been on it a lot longer than you.

Hope this helps.

[Wolfegang in reply to nomoreheels]

Yes thanks this really helps, the reason I want to switch days is because with summer coming we spend our weekends at the lake and I want to enjoy my weekends there, when I take it on Saturday I feel miserable and tired all day Sunday

[nomoreheels in reply to Wolfegang]

Wednesdays works for me too. Sounds as though you'll have a lovely summer, you'll enjoy it all the more moving MTX day. Welcome by the way!

[Hidden in reply to Wolfegang]

This is why I take mine on a Wednesday so I can enjoy the odd weekend.

[Mall]

Just miss the Saturday dose and take it on Wednesday. You won’t notice leaving the dose for a few days as it is a drug that only slowly leaves your body. There will still be enough of the drug in your body for those extra few days to be effective. What you must not do is take it sooner than at 7 day interval.

[Garnacha]

Hi Wolfegang I asked the same question a few weeks back, as the others have said either move it on a day each week which is what I did with no problems, I also changed it to a Wednesday as I was the same as you & fed up of feeling so yucky on a weekend when it was the only time to do anything as a family, enjoy your weekends at the lake x