Week 7 some plus moments but nausea and diarrhea not great 2-3days after taking it. Got a review next week so hoping can change to injection. Fatigue still a big thing which I hate. Breathing seems to have changed to so need to talk it out but then been pushing myself to walk more and climb stairs more.
I also started to drop Predd down to 3mg a day and pregablin to 1 night and one morning so wondering if this is causing changes too.
Have a great weekend all x
Love your peed & prevailing! Prednisolone & pregabalin perhaps? Autocorrect has a lot to answer for! I don't know how many times I’ve had to go back to correct what it believes I meant! Anyhow, have you asked if you can be prescribed an antiemetic, just to help the nausea subside & loperamide (which you can buy otc) to ease the diahorrea, at least those can usually be helped easily. Or, just until you change to injections when hopefully they'll be gone.
Fatigue could be a combination of lack of disease control & work, you've been busy & add in the stressful situation you’ve had to contend with recently, it will all add to how you feel generally. Also, you're tapering pred so missing the good side of what they can do. You're going through med changes, it's rarely easy.
Definitely mention the change in breathing, it is something we have to report when on MTX as it can have an effect on the lungs. It may not be due to that, it could be related to you changes in steps per day & stairs if they're not something you've done regularly & just coincidental. Your Rheumy should check you over, see if he thinks it's necessary to order imaging & respond accordingly.
The pregabalin needs adjusting to, this is why we start on a low dose & titrate it over weeks, plus it may be at fault as far as adding to the diahorrea is concerned, even concentration can be impaired. Remember it's a Class C Schedule 3 med, they're not Smarties. But you're prescribed them for a reason, they just need getting used to.
You're doing so well holding down the job you love, it can't be easy with all these changes going on in your body, including the meds that can have such an affect & take time to work on the disease. So a big well done. 🤗
ahhhh auto text just changed too tired when I wrote it to check!
Hi Deeb2908 - hope things level out soon. When I was on Pred, things were better, I could function at least, however, as soon as the dose reduced, I felt symptoms creep back. So quiet possibly the reduction, do speak with your Rheumy. Take it easy and enjoy the weekend too. Hessie 😌
I did the mtx injections and did not have nausea, some fatigue, but not too bad. My problems were bad depression and hair loss.
I'm on my 12th week of methotrexate 15mg orally and the last 4 doses have been nausea free. However I seem to be more tired but I am seeing a specialist about some kidney issues.
It all gets a bit confusing as RA is different for each one of us. My pain levels seem to be dropping a little .
Depression comes and goes but no hair loss for now.
I am a bit low the day after I take methotrexate but I can handle that. My knees have improved too. They were collapsing from time to time. Methotrexate has been my wonder drug in the past.
I had to go off it for a year due to a bad accident and a wound that needed to heal .
My feet are my biggest problem but I was told that is osteo.
I was a nurse and always had sore feet.
I've had RA for 26 yrs.
Hi Deeb, I was on mtx tablets for a while but they really never agreed with me, went onto injections and got some improvements, I am now on Rituximab infusions, magic.
Hope this helps
thank you I am requesting njections to see if this helps will take a month to get set up but think this might be the way forward.
I hope so! The injections are simple to use and painless and should improve things for you, I have IBS that gives me an upset stomach and I think it was that which made Mtx difficult for me to take.
Hope things improve soon
Best regards
Starting the mtx injections this week
Baricitinib - 7 weeks
MTX
