Hi all. Have just been reading that research is being carried out on the possibility of using faecal transplants as a treatment for RA in years to come. Not that I'm thinking of trying it!! But just wondering if anyone else has read or knows anything about it or has any opinions?
RA and faecal transplants in the future?? : Hi all... - NRAS
RA and faecal transplants in the future??
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Dobcross1
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That idea absolutely stinks!..I don't care how successful it might prove to be, there's no way that I'm having someone else's feces put inside me full stop! Besides I have enough trouble with constipation as it is! 
Haha that's made me smile😁
in reply to Dobcross1
It made me feel sick!!!
😂
NICE support faecal transplants in certain circumstances, usually for people with c-diff infection. Some success has also been reported in chrohns and other inflammitory diseases too...so maybe...if you could prevent further joint damage ?!
Folks with RD are particularly at risk from c-diff problems due the amount of ppi's and antibiotics we take, both of which alter our bowel flora. Less than 50 % of your body is actually your own cells ! The rest, your biome, is something around 53 % of bacteria fungi and other organisms. So you are make up of a lot of other stuff too, a lot of you is @#t anyway !
But I believe scientists are looking at trying to produce a more palatable concoction a medically produced alternative to faecal transplant. ( probably wont be as good 😉)
💩💩💩💩💩
Doesn’t bear thinking about 😂😂💩
More than a joke😉Have heard many interesting things. Here some reading.
I've read quite a bit that suggests that it could be promising, particularly as a support to help make sure drugs work for you. So with that and vagus nerve stimulation the treatment for RA in 20 years time might be as dramatically different as it has been over last 20 years.
What I've not got my head round is whether this can be a permanent solution...? For example if you eat a rubbish diet, and take heavy duty antibiotics then your microbiome is likely to be quite poor. So after a tramsplant what's to stop it getting bad again if you are still on same regime?
Do you know if there's solid evidence that someone on poor diet and taking high antibiotics is more likely to encounter problems than someone on a good diet taking the same antibiotics?
Probiotics, fermented foods and high fibre all help promote good gut bacteria. Probiotics should be eaten at a different time to taking the antibiotics to avoid killing them off.
Refined sugar increases the 'bad' bacteria and can upset the balance of the gut, so should be avoided when on antibiotics. Probably best to avoid refined sugar as much as you can , says her who has eaten some chocolate (I don't have a sweet tooth, just took a fancy to chocolate today!)
Yet I've also heard that fermented foods and probiotics don't do our stomachs any favours, quite the opposite in fact. I'm not well read up on foods, supplements etc, well I am a bloke, but it all seems like a bit of a minefield to me as to what's supposed be good for you and what isn't. How many times have we been advised to avoid certain foods then years later there's a change of mind and we are told the opposite...I think egg yolks is one example. It just seems to me that no one really knows. That said, I have my suspicions that chemical pollution in the environment, plus additives in processed food are the biggest culprits for doing us harm.
You sound like my wife, she expects me to believe that she only eats chocolate every other sunday.
Absolutely, I'm not a big fan of food fads, and probably our stomach acid kills off a lot of what we are meant to gain from probiotics. Some folks say fermented foods are inflammatory, and so it goes on....if you believed everything you read you would not eat anything.
But refined sugars do seem to be a problem in more than one way...weight, empty calories, alter gut bacteria, rot teeth....but I eat healthy and the odd but of what I fancy.
A good mixed diet is probably the way to go, but have said you don't like trying new foods ?
I have been drinking a little bottle of probiotics every morning for a month to see if it helps my IBS, I have stopped running to the toilet and have been able to eat a salad for lunch for just over a week, before if I ate salad I would have stomach cramps and have to run to toilet! So I feel better since drinking them but I don’t know if it is all in the mind or they actually help.
hi, my hubby suffered I b s, and since listening to Milke Sealey on youtube, he has cured himself, he s on no medications anymore . Worth a try. xx
Not read anything solid in relation to RA.....but will add it to my list of things to keep an eye out for. There is quite a bit of work that concludes that being overweight is likely to mean you won't respond as well to the drugs, and are likely to have worse problems as well as being more likely to get RA in the first place. BUt you can have a great diet and be overweight so I don't think you can extrapolate one from the other.
There's general research on microbiome that does show that antibiotics and restricted diets do have a negative effect on the number and range of bacteria in your gut.
Ok, thanks helix.
If you really think about it a shed load of medications come from humans, like infertitily drugs (Danish Army ) and RC Covents in various European Countries and if its so bad to think about would you refuse blood or a kidney. I'm sure they will make sure its not going to be just dropped into the loo then gathered and whacked in ! and if it could work then worth taking a chance. Not only that if you did'nt know how or what the begining product was would it matter.?
I think it's a really interesting idea.... one major field fecal transplants has been used in is the treatment of Chrohn's disease and other inflammatory bowel disorders. It has been shown that a rise in a specific species of bacteria in your gut may lead to some of the gut-related conditions, so a fecal transplant is a pretty good way to introduce bacteria into your gut in proportions that are known to lead to gut health.
For use in RA, I assume we;d have to first learn of a link with the microbiome in our gut contributing to disease which (I think?) hasn't been shown as yet. But, for example, if we knew that a lot of Shigella bacteria were disproportionately in the guts of people with RA that kind of thing would be a start, and the aim of fecal transplant would then be to introduce healthy populations of bacteria into our guts to compete with the Shigella.
In terms of how long these things last.... depends on the root of the problem? Could only be a short term fix (even if instantaneous) if the reason for your abnormal gut microbiota is environmental and you keep the same habits. If reason is genetic, may need repeated transplants. If reason is infection which has knocked your microbiota off for some reason, may be more long term effect having a transplant? Who knows - maybe it is a bacteria that causes inflammation in our guts initially and then leads to a cascade heading for joints? All to be discovered....
I think fecal transplants are really smart - take what works and put it where the problem is!
Thanks you've made me really think about this more (as have all the other interesting replies on here) and raised a lot of questions. Imagine if a permanent cure could be achieved in the future - even if people's habits/lifestyle had to change it would be worth it. However research seems to move slowly so whether it will be in my lifetime I'm not sure. I don't know whether RA research is less well funded than other forms but progress seems to be a little slow (I'm on MXT with not much hope of being given biologics if it doesn't work and MXT has been around 30 years I was told!).
Just got into uni this morning and the people in the office just next door are working on RA... research takes a while for sure, but we'll get there! I hope the benefit reaches you. Methotrexate has been first line treatment for ages, yes.... I'm on it too!
Reading this while eating my breakfast yuk! Might read again later!!
Hello again finished breakfast! just have to wait and see how research pans out I think.
I know it has been very successful for some people, there is some information about it in the Clever Guts Diet book by Michael Mosley.
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