There is lots of exciting work going on with the genetics of RA and trying to pinpoint which people are more likely to respond to which drugs - that is trying sort out exactly which part of your immune system is affected so it can be targeted more precisely. And this depends on your genetic make-up - which you inherit from your parents.
There is some information on the NRAS site about this.
I don’t know Kathy but am same as you, no one we know has it in family going way back, just me & yet my lovely bro has recently developed joint symptoms. Best I’ve read is that you can have genetic predisposition (? in our case 🤔) but it needs environmental trigger to set it off.
Hope not too lovely but every sore throat her joints are sore .
I no that can happen .but her knees and hands seem to swell often .as with me they took years to diagnose wouldn.t want her on these meds .thanks lovely xx
Probably so many different factors that play together. Have understood that genetics plays a 30% risk. Other factors have to exist in order for the AI disease to break out. Stress seems to be one other factor both internal and external.
well on my Dads side my gran had it ,she was bed ridden in the end, I wasn't brought up with my dad, so only knew her when I was 16 and then your in your teens so not interested in old people and I didn't know her really.
I have fibromyalgia as well ,before this year being told I have RA too now, I got intouch recently with one of my half sisters on Dads side she has fibromyalgia too, so I warned her about not switching RA on with life style, if it was that, that did it?
my son has autoimmune problems with food and carrys EpiPen
I have always had a funny immune system, never could wear things that wasn't gold or silver, hair dyes, bad stomach on some foods, things like that really before now RA
Don't know if it's all connected Keeta but my Grandfather had RA , my Aunties got Psa and my cousin, my Mums got OA and Osteoporosis all on my side so I think there could be a link in there somewhere xxx
As did my grandfather. At least I'm pretty sure he did as illness was rarely talked about in my family back then. He was sat in his armchair most of the time and used to shuffle his feet when he did try to walk. He must have been in a lot of pain but he was a tough retired coal miner and never showed it.
Mine was definitely inherited. My maternal Grandmother, 3 Aunts and my sister all have RA. I was the last to be diagnosed. My Mother doesn't have it though.
I didn.t really no my dads side.but i do remember his mum was a very small lady .and i seem to remember she had OA. And struggled with it. My older sister had both hips replaced .my younger sister has thyroid problems like me.
I'm the first in my family that we know of who has RD, but many of us are 'atopic' ...meaning we have a number of sensitivities such as hayfever, prone to skin rashes, get runny eyes and a cough perfume/chemical smells. One also has asthma and psoriasis.
There is a complex genetic link to RD, but environmental triggers such as stress or illness usually set it off.
I'm the only one of my siblings to have RD, hayfever, allergies, asthma etc. My Dad had multiple allergies which worsened with age and that's it. There is asthma and exzema in my children and grandchildren but, so far, nothing worse thank goodness. Short answer is blowed if I know but wish the scientists would find the causes soon.
My mother had it, a maternal aunt had it, and a paternal cousin has it. I suspect my sister has it but she refuses to visit a dr now because she was told 30 years ago that she didn’t have it.
I’m seronegative as well. My liver is affected, otherwise I think they would dismiss me too as my blood is good except the liver tests and a very special test they run once a year for different inflammation markers. My cousin who has it is a dr himself. I believe it is a hereditary gene that is triggered by stress or trauma or other illnesses.
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.