I just started this drug last Wednesday July 11, 2018. All I can say good about this drug is my pain from RA is a little better. The inflammation I have been experiencing for years is better. With that being said, on Wednesday when I got the shot I felt lightheaded within just a few minutes of taking the shot but I was otherwise ok. That afternoon I began to have nausea pretty bad and it continued until yesterday which was Saturday. In the late afternoon Saturday, I began to have a stomach ache. It continued until I finally went to sleep. I woke up this morning, Sunday, and the stomachache is still there but much worse than yesterday. The stomach cramps are awful! It is accompanied by diarrhea and I am not feeling well at all. I am going into my doctor tomorrow and I am not taking any more of this medicine. It is evil! I’m sure it works for many people, but for me I’m not ever taking it again. Good luck!