Methotrexate alone

[Bookworm55]

Are there people out there whose seropositive RA is under control on methotrexate only? I was put on hydroxychloroquine and methotrexate at diagnosis in Feb 2016 but have just had to stop the hydroxychloroquine due to eye problems. (Posted about this about a month back).

I see the rheumatologist in mid-Sept and wonder if I will be offered something to replace the hydroxychloroquine. I have already reduced my methotrexate from 20g to 12.5g due to side effects.

Do people find methotrexate alone works? I have not noticed any deterioration in my condition yet but it is of course early days.

[Elmo333]

I have seropositive RA and am currently only taking methotrexate injections but I’m not at all very well controlled so I have a box of hydroxychloroquine in the cupboard which I haven’t started yet. I had to stop it many months ago but I can’t remember why (!) so I’ve been told to start it again. I’m avoiding it but I will have to do it🙄

[Bookworm55 in reply to Elmo333]

Thank you.

[Nsmith13 in reply to Bookworm55]

I'm just on mtx and hydx but I have steroids low dose as well but I still have a lot of fatigue pain and a bit of swelling I've tried bio but they didn't work was worse !!!

[aramire1]

I am seropositive and am currently on just methotrexate. I was diagnosed in November and started oral mtx then. So far so good...as of February when i had my last appt i am in remission! I did have a flare in my shoulder last month that lasted about a week but besides that I’ve been pain free since about early January.

[Hidden]

Yes, I am sero positive and controlled at last with injections of methotrexate.

I started with sulfasalazine, was good but my liver wasn’t happy. Plaquenil for a couple of years and with an increase developed a severe rash. However on tablets for a number of years I was never really controlled, now on injections all good and “touch wood” finally inflammatory markers are normal. So yes my rheumatologist has left me just on the methotrexate.

[Bookworm55]

Thank you .

[AgedCrone]

I have Sero+ RA, & I was really well controlled on Mtx only + FA for seven years.In fact I have never taken more than on Dmard at a time .

I've now been on RTX (no Mtx added ) for two years & I am doing well.

So trust your medical team.....you could well only need the Mtx.

[Bookworm55]

Many thanks to everyone- all experiences very valuable. I’ll see what rheumatologist says in Sept - and may well post again!