After several months of indecision I have taken the plunge and started baricitinib today. Thought I'd made up my mind not to start it, but after talking with my rheumy last thursday, for better or for worse, I've decided to give it a go. Just hope I'm not opening myself up to a serious infection again as I've not had one since stopping all immune suppressants nearly 2 years ago. Even more of a worry, according to my chest consultant, is there's a possibility that baricitinib could further deteriorate my already RA damaged lungs. On a more positive note, and again according to my chest consultant, there's research going on that JAK Inhibitors might be beneficial for people with asthma and COPD...all digits crossed on that one!
You can probably see why starting baricitinib has been such a difficult decision for me to make, ie. do I put up with constant pain (not much fun but I can handle that for the most part) and further joint deterioration..my hands and feet are already pretty bad. There's also a risk that my raised inflammation levels could also cause my lungs to deteriorate, although there seems to be some uncertainty about this and they could deteriorate whatever the case. In fact, the more I find out about this awful disease the more I realise how much uncertainty exists.
Back to the BARI, rheumy has prescribed one month's supply of half the max dose - 2mg tablets, which are odd shaped pinkish little things. Next step is to report to the rheumy sec in two weeks time to let her know how things are going and whether or not to prescribe more baricitinib.
edit...forgot to add that around the same time as I contact the rheumy sec, I have a FBC taken, plus a blood test for HIV.
No doubt after reading the above you can tell how anxious I am, so wish me luck, plus keeping as many fingers crossed for me as you can won't go amiss either.