Hi all, its been a long long time since I have been on this site but I always get comfort and help from it when needed. My RA has been under control for almost 6 years but the past year it has been trying to rear it's ugly head again in one joint or another. So my Rheumy doc suggested adding in Leflunomide (20mg), (currently on 25mg MTX injection, hydroxy, folic acid, thyroxine, vitamin D)..... Holy sh-t!!!! my body does not like LEFLUNOMIDE I became quite unwell immediately upon starting it but could not quite put my finger on it. I just did not feel right. My appetite diminished, I felt quite sicky,had what I thought was a rotten cold that lasted for weeks and when week 5 came around boy did I have chronic diarrhoea. All very unpleasant symptoms. Then if that wasn't enough 6 days ago I could not stand up when getting out of bed continuing for around 2 hours with pain in my lower back/thigh/groin left side that was excruciating. Now 6 days later and a cupboard full of pain killers/naproxen/heat/ice therapy and a barrel full of tears it has now settled but still grumbling upon waking.
It's a public holiday here in Scotland for some of us so I am waiting until tomorrow before phoning my RA nurse for advice. I did speak to her before my sudden back pain and I was told to pick up a new script for the reduced dose (10mg) leflunomide but the sicky feeling and chronic diarrhoea is still there - I do not want to take this drug it clearly is affecting my gastro works.
I'm thinking my sacroiliac joint has been inflamed (all the research I have done suggests this) and the reason for my post is I am wondering if anyone on here has suffered with this joint and similar side effects from leflunomide and if they are related. (2 years ago I also suffered a herniated disc (L5S1) but the pain then was all in my left leg nothing in my actual back and I know this time around it is very different so I am ruling out the bulging disc again but hey without an MRI who really knows)...........
Thanks for listening.