Has anyone experienced altered moods on humira?

[Am2873]

Hi all, I've been taking humira for 10 weeks now, still not seeing any benefits as yet ☹ still stiff for up to 30minutes every morning, still inflamed, still sore. What I have noticed is, mentally, I'm struggling, my moods are so low or I'm really angry! This is really uncharacteristic for me. I'm normally the happy go lucky calm one! I suffer with anxiety and have had bouts of depression (I still suffer with the occasional wobble!) This definitely feels like a prolonged wobble! I'm taking humira along side 20mg of mtx. Just wondered if anyone else has experienced mood disturbances or if I should give it more time? I did my jab on Wednesday, by Thursday I'd had a screaming row with my OH over gardening 🙍‍♀️🤦‍♀️ to put this into perspective.... the last time we argued was 7years ago!!! Seriously... We don't argue! I've been snapping at my kids, can't be bothered with anything, tired all the time and can't sleep or sleep too much! If you've got this far, thank you! Any similar experiences or advice would be gratefully received xx

[MarshaM]

I am on Humira, MTX, plaquine and have not felt depression or mood deviation that I've noticed. I play tennis and volunteer at our local animal shelter fostering kittens, so I stay busy.

[Superfloozie]

I had lots of mental issues with humira so much so that I stopped taking it after 3 months which was gutting as my joints were amazing! Don’t know if it’s worth you not taking it for a week and seeing how u are? Before flagging and failing via rheumy?

[Am2873 in reply to Superfloozie]

Thank you for your reply x I think that's exactly what I'm going to do. It's so hard to work out what's the meds and what's actually a condition rather than a side effect sometimes! X I hope you found an alternative that works for you x

[Matalow]

Sorry to hear 👂 your having such a rough time. I think it’s time to get in touch with your Rhumy it may be that the Humira isn’t for you, although I had to come of methotrexate as it wasn’t for me.

Hope you get sorted soon for your family’s sake as well as yours.

Regards Mike

[Am2873 in reply to Matalow]

Thanks for your reply x yes I think you're right, I'm going to miss my next jab first to see if there's an improvement in my mood and take it from there. I am on mtx too and hate the stuff! Unfortunately it's a requirement of the hoops we have to jump through to get successfully funded for biologics in my area, even though, in my opinion, there's little to no benefit for me x

[Superfloozie]

It’s so difficult to make a judgement, I’ve been on 6 different biologics and have had really awful side effects on 4 of them☹️ Humira was so so good for my disease that in 20/20 hindsight maybe I should have tried for longer and seen if the side effects got bette, I’ve been on Stelara now for 2 years and the initial 5 months were shocking but because at that point there was no other option I powered through and the side effects got better. But you’re not getting much relief either, I think by 3 months it should have made a difference although I know 6 months is the ideal length. I would definitely miss a week, see how u feel, how your joints feel and go from there. Weirdly a lot of side effects can be helped by taking vit C in quite high doses, 1000mg a day may help. Always worth a shot! Good luck with it.