Sulfasalazine and weight gain: Hi all Hope your having... - NRAS

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Sulfasalazine and weight gain

Kyriew profile image
7 Replies

Hi all Hope your having a nice relaxing bank holiday. Wondering if anyone has found they have gained weight whilst taking sulfasasazine. Ive been on them for 8 weeks alongside my other meds Methotraxte and hydroxychloroquine and have gained 6 lbs. I dont think my eating habits have changed dramatically but am wondering if there is a connection.

xxx

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Kyriew profile image
Kyriew
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hawker955 profile image
hawker955

There is no reason why an antibacterial combined with aspirin like Sulphasalazine should cause increased weight. RA will if your activity level falls though.

Cornishrex profile image
Cornishrex

Yes I did. I track my weight and diet quite carefully being an ex weight watchers dieter. I've been on Sulfa twice now. Came off both times due to reactions. the second time I went on it I realised I had put on about 6 pounds in weight. I couldn't understand why. I looked back at my records of what happened the last time I tried sulfa and again I found that I had put on 6-7 pounds in weight. And then when I stopped it I lost that extra weight over the course of the four following weeks. I didn't make the link last time around as it spanned the xmas period. This time however, it's a bit too much of a coincidence. I did a bit of research and found a lot of other people on the internet saying similar things. I've only just recently come off it again so I'm watching with interest to see if those 6 pounds come off again in the same way. I was on sulfa for about 8 weeks each time. I'm a healthy 23 ish BMI and I never usually move by more than a pound or 2.

MimiXallBoys profile image
MimiXallBoys

YES, I have put on 18 lbs. over an 8 month period, since beginning Sulphasalazine. But as a passenger in an automobile accident 19 years ago, I suffered multiple life threatening physical problems. One of those being a Severe Traumatic Brain Injury. Was finally released from Hospital after 6.5 months (weight was down to 82 lbs.), and transferred to a Full Time Rehabilitation Facility for 4 more months. Had to learn to walk, talk, read, eat, drive, well....EVERYTHING all over again. Due to the TBI, I have not had an appetite for over 18 years, along with the inability to sleep without medications. With absolutely ZERO CHANGE in my appetite and/or eating (or lack there of), I have put on this 18 lbs. since beginning this medication.

Thankfully, my two grown daughters are now VERY HAPPY with my weight! Although I am not used to weighing over 130 lbs., I FINALLY have MUCH LESS PAIN!!! This medication, Sulphasalazine, has been a COMPLETE LIFE CHANGER for me! Extra weight is fine by me, when I now can do dishes, wash laundry, run the vacuum cleaner, shower and wash my own hair without tears!!!!

Kyriew profile image
Kyriew in reply toMimiXallBoys

Wow you been through a lot. Happy to say my weight gain has stopped but I am finding it almost impossible to lose any weight. At only 5ft 3inch I weight 14 stone. I too have found the Sulphasalazine really helpful. Still get a bit of pain but nothing like I was having. xxxx

Kyriew profile image
Kyriew

I am seeing my Rhummy next month I think I will see what he says I really want to lose some weight having gone from size 12/14 to 14/16. Unfortunately I find exercise really hard to cope with so I have no doubt that is also an aspect to add in. xx

Taxlady profile image
Taxlady

I lost 280 and maintain the weight loss but after I started taking this drug I gained 9 pounds

Gerriemom profile image
Gerriemom

Yes! I put on 10 lbs in 5 weeks then another 6 lbs. My diet has improved a bit but I'm inactive due to hip problems. But I've been inactive the 2 previous years due to other surgeries. My doctor didn't believe it was the medicine. I'm vindicated!

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