I take 10mg methotrexate weekly, no other meds. I've got a really heavy cold, sore throat etc so didn't take methotrexate last week. I've only missed once before in 5 years. I'm still unwell this week so thinking of not taking for a second week, but I've never done this before. Is not taking meds for 2 weeks ok or am I running the risk of undermining all the good work the meds do for me?