aftert 6 weeks of having the sore throat my GP referred to ENT as above, I was told to stop the omeprazole and start taking lansoprazole 30mg morning and night, this has made no difference and I do not believe I have acid reflux. I read that omeprazole can increase the side effects of metho, one of which is constant sore throat. just had appointment with rheu consultant who thinks it may be the metho. anyone had this, please let me no, this is having a serious impact on my day to day life, as if having RA is not enough!!!