My mom have extremly agressive RA. This november she took her two rituximab infusions. After that she felt her RA symptoms became harder and even steroid prior didn’t help her. Now we have 2 weeks after 2nd infusion passed and mom feels more and more bad, pain and weakness keep growing. We know mabthera is slow med and sometimes it takes 2-4 months before you feel emrovement. But I worry about that initial aggravation. Did anyone experience the same?