Hi everyone. I wonder if you can help me. Following my diagnosis in April I am on now oral MTX 22.5mg weekly. And I have to say it is definitely doing a great job with my joints. I still have a couple of tender knuckles and slightly swollen feet but am much much better than I was. However I was expecting that the fatigue would improve too, and it just hasn't. I am absolutely hanging nearly all the time and have even had to have a sleep some mornings. I definitely can't get through any day without a kip. If I try I end up brain dead and terribly irritable by late afternoon and just can't function. Should I be expecting the MTX to sort the tiredness out too ? I am also slightly anaemic but struggling to get a decent dose of iron from the GP. So I need to understand wether it is more likely to be the RA than the anaemia. Has anyone else found the tiredness persisting even though the joints are responding well?
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