FDA update for Evusheld: I hope everyone... - Kidney Transplant

Kidney Transplant

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FDA update for Evusheld

Transplant2018 profile image
10 Replies

I hope everyone who is immunocompromised is aware of the FDA update that Evusheld may not be effective against the emerging Covid subvariants. Our current Evusheld antibodies provide protection against the current variants of BA 4 and BA 5. Those same Evusheld antibodies do not neutralize new subvariants such as BQ.1.1, and thus we are no longer protected. As those new subvariants become dominant, it is important not to rely on Evusheld for protection from serious illness. This is extremely discouraging but important information.

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Transplant2018 profile image
Transplant2018
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10 Replies
Oceansideup profile image
Oceansideup

It’s so important to have the latest information. Thanks for sharing.

Gardner-NY profile image
Gardner-NY

Thanks for writing this for all to read. My spouse who had a transplant was not able to obtain this Evushield. I read in an NBC news article last night that around 600,000 doses of Evushield were produced though there was a need for 7 million. The article stated that unless drug companies push to do more research on the next medication to help immunocompromised people and produce it in the proper numbers, this group will be living more isolated. Already my spouse and I have been living isolated for close to 4 years. I wish there were easily to obtain medications to help all who are immunocompromised. I wish you and everyone well as the new covid19 virus continues to change. About 4% of Americans as of late Sept have gotten their new booster shot and I keep meeting people saying they don't plan to get it. THis is all alarming. Keep yourself well.

JackN profile image
JackN in reply toGardner-NY

Are you aware of covidsafe.fyi/evusheld/ which lists Evusheld availability across the country? There seems to be a lot of available doses in MA.

Porter20 profile image
Porter20 in reply toGardner-NY

I had this shot after transplant and Covid shots to get my transplant & one booster.

I still caught Covid in Sept. 2023. They were out of monoclonal antibodies. I had a transplant because Covid took my kidneys and gave me short term heart failure. I had a transplant 12/21. When having Covid in 9/23 I had nothing medication wise and got over it fine. It was like a bad cold. I did reduce my myfortic dose. Did not even need to go to the doctor just called them.

Blessed!🙏🏻

Hope this lessens fear!

So fear not

RAM99 profile image
RAM99

I live in MA and got the Evusheld last week. But, it was not a pleasant experience on many levels.

First, none of my Drs seemed very educated on what it was, or how given, etc. I got lots of vague answers, but all said I should get it as a transplant patient, so I went.

Got to the IV lab not knowing what to expect and was handed a four page info sheet AS they were sticking an IV in me, and while I was trying to ask questions...

"Experimental medicine, not FDA approved with unkown reactions, except a high rate of heart issues...and that was just the first paragraph...

AND, you must geit every six months on top of each new vaccine...

I never feel well, but have not been great since that day. Thus, I ll not be getting another dose(one needle in each butt cheek...not fun)

I am hoping that the medical world does not forget all of us and someday we will have a vaccine, or something similar, which gives us real protection.

Safe days to you all🤗

Porter20 profile image
Porter20 in reply toRAM99

Mine was a shot in each butt cheek given only once.

donnabethme profile image
donnabethme

Had heard That’s very discouraging.

KathleenMA profile image
KathleenMA

I saw my nephrologist last week and asked about getting my 2nd dose of Evusheld knowing it’s not as effective against new variants. She checked with infectious disease and they are still recommending it for transplant patients. When I got my first dose in May, I was not put in an IV, curious what that would be. They took my BP before the shot in each butt check then checked my BP 3x every 20 minutes. I had no issues and no side effects after.

Transplant2018 profile image
Transplant2018 in reply toKathleenMA

Evusheld is still recommended because it is effective against BA 5, but it won't be effective against the new subvariants that are in the process of overtaking BA 5. But it's good you got it as it will be helpful, at least for a while.

Oceansideup profile image
Oceansideup

I received Evusheld shots in my arms and no IV. Waited 15 minutes to make sure I had no reaction, no worries. Also make sure I get the latest booster. Until we have more options, staying boosted and taking precautions is the best we can do.

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