Does Evushield work immediately???

[Powerfalcon]

I received my two shot Evushield monoclonal antibody shots this past week. I am a 62 year old and received a transplant in 2019.

I have been getting mixed messages about when I am protected. Is it immediately or is it like the vaccine and takes time?

If anyone knows I would love to hear from you. It will make a difference on my travel plans in a week!

Had only one side effect. I was tired for a day . Thanks.

[Transplant2018]

On the recent John's Hopkins webinar, I believe it was stated that it takes two weeks.

[Eyak1971]

I like you had several questions. I didn't receive any documentation after the shot. Whoever the company was that produced the medication should have done a better job. This lack of follow through causes hesitation to actually get the shots.

[Powerfalcon in reply to Eyak1971]

The company is AstraZeneca out of Wilmington Delaware. Thanks

[Eyak1971 in reply to Powerfalcon]

Thanks for info. Take care.

[DexterLab]

I am getting tested in two weeks to see if I am a candidate for Evusheld, despite having 4 Moderna jabs. I just looked at the Evusheld prescriber sheet, and it does not give a specific number of days. The summary of the clinical data looked like about a week for it to kick in. Since it is a monoclonal antibodies, not an mRNA vaccine, the timing may be quicker than for Pfizer or Moderna. I did not find a clear answer.

[WYOAnne NKF Ambassador]

I received an information sheet when I received my 2 shots of Evusheld the end of January. It takes about 2 weeks for it to become effective.

So did you receive the new dose of 300 mg of each? This is the new dose approved by the FDA.

I had to go back this last week for an additional 150 mg of each. 6 months from now I will need to return and receive 300 mg of each.

I am 22+ years post transplant

[2/24/2022] The U.S. Food and Drug Administration has revised the emergency use authorization for Evusheld (tixagevimab co-packaged with cilgavimab) to change the initial dose for the authorized use as pre-exposure prophylaxis (prevention) of COVID-19 in certain adults and pediatric patients.

Based on the most recent information and data available, Evusheld may be less active against certain Omicron subvariants. The dosing regimen was revised because available data indicate that a higher dose of Evusheld may be more likely to prevent infection by the COVID-19 Omicron subvariants BA.1 and BA.1.1 than the originally authorized Evusheld dose.

Previously, the authorized Evusheld dosage was 150 mg of tixagevimab and 150 mg of cilgavimab administered as two separate consecutive intramuscular injections, with repeat doses every six months while SARS-CoV-2 remains in circulation. With this EUA revision, FDA has increased the initial authorized dose to 300 mg of tixagevimab and 300 mg of cilgavimab. Patients who have already received the previously authorized dose (150 mg of tixagevimab and 150 mg of cilgavimab) should receive an additional dose of 150 mg of tixagevimab and 150 mg of cilgavimab as soon as possible to raise their monoclonal antibody levels to those expected for patients receiving the higher dose.

[forthelonghaul]

Hi.I was told it takes two weeks. I planned my trip home around it.