update on ozempic: i was prescribed ozempic... - Kidney Disease

Kidney Disease

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update on ozempic

S_dillow profile image
44 Replies

i was prescribed ozempic 2 mg last week and noticing a pain in my left side.both pcp and nephro assured me it was ok to take.came across an article on my news feed detailing kidney damage and lawsuits as well as gastrointestinal damage.i think im going to have a chat with two doctors tomorrow.

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S_dillow profile image
S_dillow
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44 Replies
Badger2024 profile image
Badger2024

good idea. I think they wrote the script for you to be on a 2mg dose to get the fuller strength pen but I still don’t think they wanted you to jump straight to that amount. Pancreatitis pain can be pretty bad. The Ozempic instructions clearly say you must titrate so you couldn’t blame them. Get on to it fast. Use a heat pack for pain. Good luck

S_dillow profile image
S_dillow in reply to Badger2024

thanks.they never told me about going from a lower to a higher dose at all.

Ingoodhands profile image
Ingoodhands in reply to S_dillow

I agree with Badger and Basset. My pharmacist of 10 years knew i was having it for the first time, she voluntarily came to me and advised on the 0.25 dosage weekly for the next six weeks. 1.25ml divided by 6.Dosage adjuster is there. You can rotate and set it to 0.25. I've had bigger meaner needle for my psoriatic Arthritis, and this needle is so tiny, i am still not convinced if i had injected it because i hardly felt the prick. I have to agree with you on the article that you read. Not the same, but an 80 year old lady and a 60 year old's kidney condition worsened after being on Ozempic.Link is here. Don't panic! We need to educate ourselves that's all!ncbi.nlm.nih.gov/pmc/articl...

barbara55109 profile image
barbara55109 in reply to Badger2024

These pens aren't adjustable. That's why there are different dosage pens. It takes six months to get to 2.0!

barbara55109 profile image
barbara55109 in reply to barbara55109

I think it depends on the country you live in and the type of pen. None of my Mounjaro pens were or are adjustable. One pen, one dose. Some of my ozempic pens were adjustable with 4 doses a pen and others weren't. In some countries people get a bottle and syringe, like old fashioned insulin bottles.

CuriousCKD profile image
CuriousCKD in reply to barbara55109

YES!

Bassetmommer profile image
BassetmommerNKF Ambassador

What Badger said.... exactly. You are supposed to start at .25 and go up over many weeks of time. I started at .25 and was on that for a long time. Then went up to .5 and had two major pancreatitis tacks. Went back down to .25 and have been there for over a year or so with no pancreatitis. I had pancreatitis before, years ago when my gallbladder was in terrible shape. Had that removed and did not have any more. I would immediately call the doc about starting at a lower dose.

S_dillow profile image
S_dillow

thanks bassetnomer i am doing that today

Terrcolbert profile image
Terrcolbert

I’m on Mounjaro . I’m at 15 mgs now . The highest dosage for Mounjaro . As with all medications you can experience side effects ranging from moderate to severe. I get nausea from time to time . My daughter is on OZEMPIC . She gets a ton of nausea and vomiting. Side effects depend on the person also . What one person experiences another may not .. We’re all different . BUT it’s important for your Doctor/ Doctors to always listen to your concerns . I wouldn’t let them dismiss my concerns or ignore my symptoms .. Your Doctor needs to check you out to make sure everything is ok . I’d insist .. i wish you well on your journey…

arTistapple profile image
arTistapple

I have an inherent loathing of drugs that get ‘film star’ status. I always feel thoroughly suspicious - I guess getting caught out by a number of ‘wonder drugs’ before, have brought this about this suspicion in me e.g. Amphetamines (yes I am old enough that these were prescription drugs once upon a time and again for weight loss) giving me heart problems and Statins giving me muscle problems and yet they are ‘pushed’ on everyone. Call me biased but this drug seems potentially something we really should not be entertaining. Ask all your questions as you plan. Smart person.

phebamom profile image
phebamom in reply to arTistapple

I totally agree. My instincts are telling me this is a drug loaded with future issues. But, if I even mention it people go gaga. The CIA has a term for it; it is called "Blowback" the unintended consequences of interference. I have a cousin who lost 42# on the drug. She has a lot of gastrointestinal issues from the drug and she is starting to gain some weight back. The two kids next door to me(early 30s) are both on it. I remember fen-Phen. I also remember working nights for a local doctor in St. Louis when I was 17. All he did was prescribe diet pills. Patient after patient for scrips for amphetamines. So, like you I remember the amphetamine craze.

arTistapple profile image
arTistapple in reply to phebamom

Blowback. It’s a great description for putting your head above the parapet. However it’s an allegedly the free world and we are all subject to being misdirected from time to time. However this is particularly bad when it’s a medical professional doling out the advice and then people finding issues with it - sometimes too late. Sometimes by not trusting what our own bodies are telling us. It’s not always so obvious when we feel bad anyway to differentiate immediately. We have a lot of trust and that makes us extra vulnerable. I am sure this drug probably works for some people but already ill people are much more likely to be upset by it’s actions, rather than be helped by it. My experience is just an ‘opinion’ really because what works for one does not mean it works for everyone.

phebamom profile image
phebamom in reply to arTistapple

As I type this I am sitting in a hospital room, having finished a 3 week process call a stem cell transplant. The transplant is to treat the bone marrow cancer that was attacking my kidneys. The drug they gave me was terrifying; with a half life of just 60 minutes it completely wiped out my bone marrow, and my immune system. The fatigue is profound, the G.I. issues beyond reckoning. Think 20 depends per day. But, they have been giving this drug for 20 years, they gave it to me only to cure a fatal cancer, not because an ad on tv told me I needed. The CIA adopted the term Blowback during the first war in the Middle east because they knew the "Blowback would be more war. I like a quote by R.L. Stevenson: "Sooner or later, everyone sits down to a banquet of consequence".

barbara55109 profile image
barbara55109 in reply to phebamom

I'm sorry to hear you have cancer. I'm glad none of the Judgy McJudgersons here aren't slamming you for taking drugs to stay alive. Sometimes the choices are life and death. It isn't easy or simple. Good luck.

phebamom profile image
phebamom in reply to barbara55109

Thank you for your kind words. I only made the comparison because the very dangerous drug I was given was not a recommendation from a TV ad for me to "ask my doctor: if Melphalan is right for me. I just think a lot of people are taking these drugs without thoroughly investigating comorbidities that could have a negative impact. This is not a support group for the A1C drugs. This is a kidney disease support group. My focus is kidney disease. The group of medications we are discussing have a record of causing kidney disease in those who are susceptible. I have Multiple Myeloma. I began my MM journey with a benign condition called MGUS . I was not given Melphalan (the stem cell chemo), or the four other chemo drugs for many years. Oncology science used genuine wisdom by balancing the side-effects of chemo against the true need for a drug at that time.

barbara55109 profile image
barbara55109 in reply to phebamom

Glp1s do NOT have a history of causing CKD. They are responsible for improving my stage 4 CKD.

phebamom profile image
phebamom in reply to barbara55109

I would agree with that 100%. My female kidney doctor and my GP helped my kidneys. I think the absolute worst on kidneys are hospitalists. They have such a different sort term way of thinking about medical care. I think it is fine for people like to have your medication. But honestly, the entire "ask you dr. if this med. i right for you" mind set just promotes the sale of medications that are wrong for some people. It should never be the patient's choice to take a medication with a lot of side-effects. Not only that, then there becomes the issue of increased cost because of high demand , plus the inability of some patients to acquire a medication they truly need because the bandwagon users are gobbling up supplies. One of the young nurses who takes me for walks told me she is doing a paper on Weygovy and similar drugs. So far, the findings are grim. Patients who truly need their medication are often having difficulty finding it. Delay in proper dosage of medication puts patient at higher risk of kidney and pancreatic issues. To be blunt, I totally despise the entire" "ask your doctor if Med A. is right for you"

Badger2024 profile image
Badger2024 in reply to phebamom

In Australia it is illegal to advertise prescription drugs to the public. The US should fight for the same. Big pharma have too much power over there in my opinion

phebamom profile image
phebamom in reply to Badger2024

My cousin who is on Weygovy, has had serious thyroid issues for years. She is losing weight on Weygovy, but her thyroid and gut are in turmoil. She looks awful. I am just fearful of the long term consequences for her. I thing the A1C drugs are wonderful for those can take them and who truly need them to the point where the benefits outweigh the risks. That decision should never be made through television advertising. Doctors in the US are under tremendous pressure to prescribe these meds. This is all about big pharma making huge amounts of money . PS. Going home today, after 3 weeks in hospital. My beagle on my lap and life will be good. Am very homesick

Badger2024 profile image
Badger2024 in reply to phebamom

Agree. I’m so glad that you are now home with your beagle. Dogs are the best. I wish you well in your recovery 🙏

arTistapple profile image
arTistapple in reply to phebamom

I am really sorry about what you are going through. Strength to your elbow (a Scottish term for recovery of anything through drinking copious amounts of alcohol) definitely not to be recommended these days. However the meaning being “Good Health to you”. I love your RLS quote. Spot on!

honeybug profile image
honeybug in reply to phebamom

🤗♥️🥰🙏🕊🌿🌸🦋

phebamom profile image
phebamom in reply to honeybug

I love it, best use of Emojis I have read. Very weak, but feeling okay Can't believe I made it through, Scheduled to go home from hospital on Monday. 3 weeks since I have seen puppies. Very homesick

honeybug profile image
honeybug in reply to phebamom

Ahh bless sweetie. 🥰♥️🤗

I’m truly sorry about your suffering and I just said a special prayer for you hun. I know you miss home and those puppies…will they still be puppies as fast as they grow??? PM me anytime for a shoulder to lean/cry on. You are amazing!! God bless you. I pray you go home as planned sweetie. Love and prayers.

EJ 🤗♥️🥰🙏🕊🌿🌸🦋🐩🐾🐾🐾

barbara55109 profile image
barbara55109 in reply to phebamom

If your cousin had gastro issues her medical staff should have reduce or discontinued her GLP1 use. If she is no longer using the treatment, then of course she will gain weight back. Drugs treat medical conditions, they don't cure them. Even chemo drugs have limits on their curative properties and other drugs like Metformin are given to keep cancer in remission.

honeybug profile image
honeybug

I took it and my GI tract is permanently damaged. It’s my personal opinion that people who are chronically ill shouldn’t take it because of how compromised we are. Because of our uniqueness it will affect everyone differently so you’ll never know which area of the body will be targeted.

I’m amazed at how easily healthier people can lose so much weight. It truly must be nice that it works so great for them.

Best wishes being proactive my friend.

Love and prayers

EJ

S_dillow profile image
S_dillow in reply to honeybug

thanks.i stopped taking it,wrote my nephro who told me to talk to my pcp,which hasnt replied back.

honeybug profile image
honeybug in reply to S_dillow

most welcome sweetie. We have to b so careful don’t we? Love and prayers.

EJ

barbara55109 profile image
barbara55109 in reply to honeybug

I live a world where transplant boards consider someone who weighs 200 pounds to be in the same category as someone who weighs 2000 pounds. BMI over 40. Sorry you just don't deserve to live. BMI over 30. Sorry, you don't deserve to live either, but if you promise to lose weight and promise to go to the YMCA 7 days a week for four hours a day, we will just maybe let you live. But before we are willing to let you get on the list for a transplant you have to PROVE YOU ARE WORTHY OF LIFE BY DOING EXACTLY WHAT WE TELL YOU. After losing 50 pounds and spending every night at the YMCA I'm still overweight and still would not be worthy enough for Mayo or the U of M. I weigh less than I have EVER weighed as an adult. I weigh what I did when I was 16 years old. I could NEVER have done this without Mounjaro. MJ let me get of insulin, which I was forced to take because of CKD. I eat once a day. Most days I have a turkey sandwich. I try and try and try to stay under the 800 calories I've been ordered to stay under. It's really hard, especially since I cannot eat vegetables. I have no colon and fiber leads to blockages. I've dealt with a partial blockage for the last few days and this morning passed an enterolithiasis stone. I probably have more blocking my illum. Fiber and veggies would kill me. I have a five month wait to see a GI doc to get guidance on the enterolithiasis. Sorry for the rant. I'm sick of Judgy McJudgers who have NEVER faced the choices they are talking about.

S_dillow profile image
S_dillow in reply to barbara55109

im not bitching just trying to do whats best for me.even if i were to lose weight i have other conditions that remove me from the possibility of a transplant.i can see why youre mad but i didnt mean to make you mad at me.my pcp still hasnt returned my call but im trying again monday

S_dillow profile image
S_dillow in reply to barbara55109

im just trying to do whats best for me.even if i were to lose weight i have other conditions that remove me from the possibility of a transplant.i can see why youre mad but i didnt mean to make you mad at me.my pcp still hasnt returned my call but im trying again monday

barbara55109 profile image
barbara55109 in reply to S_dillow

I'm not mad at you. My reply was for one of the Judgy folks who said we shouldn't take GLP drugs. I get attacked a lot for taking MJ. I'm 61 and am not ready to go.

S_dillow profile image
S_dillow in reply to barbara55109

ok.i was on munjaro which was working with no symptoms and now there isnt any to be found anywhere in my area.hence the ozempic

honeybug profile image
honeybug in reply to barbara55109

barbara55109 😊🌿🌸🦋

Wowwwwww…you have a right to be angry and rant sweetie. I’m sooooo very sorry about your plight. I’m so happy for you that MJ has worked for you. I’m not judging you hun for anything. I used to be anorexic but as my 70 different comorbidities have been in constant progression (most of them are autoimmune related ) my thyroid was destroyed due to all of the pandemic stress and couldn’t get thyroid meds I’ve suffered from little sleep and multiple back injuries torn and frayed tendons and ligaments in my ankles that kept me 99% Immobile for a year resulting in severe diabetes. I’m over 200 pounds myself and doing the best I can under the circumstances. So I certainly don’t judge others I empathize with them. I hear your pain your rejection and your heartache hun. I wish I could give you an empathetic hug…I just said a special prayer for you sweetie. You take care and bless you. Best wishes hun.

EJ 😊🤗♥️🥰🙏🕊🌿🌸🦋

barbara55109 profile image
barbara55109

ALL drugs have side effects. Daily aspirin gave me stomach bleeds and anemia. Prednisone destroyed the bones in both knees and ankles and I have chronic pain and low mobility as a result. Mounjaro is controlling my diabetes and helped me lose weight so I could qualify for a kidney transplant. Judgy anti drug people make sweeping statements, like I would NEVER take a particular drug. Each of us need to make informed choices. It's awfully easy to say you'd rather die at 30 than take Prednisone or die at 61 from kidney failure. Until your life is on the line you really have no idea what you'd do. I fight misinformation about glp drugs because there is a lot of it here. They are miracle diabetes drugs. They do work. Like many powerful drugs there are known side effects. All the lawsuits will get tossed because they are over known side effects on the label. Like all drugs, severe side effects are know, but rare enough they get FDA approval. If severe side effects were common, they wouldn't get on the market.

S_dillow profile image
S_dillow in reply to barbara55109

thanks barbara

WildIris profile image
WildIris

My ex-husband is on ozempic, carefully titrated dose and is doing fine, has lost significant weight, no complaints, just to offer a maybe more typical example. He is in permanent afib, has mobility issues, no kidney issues.

barbara55109 profile image
barbara55109 in reply to WildIris

Yes, it is far more typical to not have severe side effects. Under a Dr. care, with carefully titrated doses is the prescribing protocol. Serious, but rare, side effects come with every single drug out there. Including OTC drugs.

FelineFandom146 profile image
FelineFandom146

Hello: I don't trust Ozempic. Too many bad side effects mainly Stomach Paralysis, GI issues. My spouse is on it for Diabetes. There should be a caution on it. I don't trust any new drugs. Many are recalled after being given FDA approval. Is the pain in the left front side or back. As another said, Pancreatitis could be an issue. You can also check in with your Pharmacist, too. They know more about meds than physicians do. Have you tried Trunature Advanced Strength CinSulin 500mg., 200 Vegetarian Capsules yet? It is available on Amazon and at Costco. My spouse has tried it with good success, as have many people. It is not a a drug nor a magic pill but it does seem to help diabetics naturally lower sugar levels. Some have been able to get off insulin altogether. I advised my spouse to slowly lower his Ozempic dose week by week while on the Cinsulin and watch his glucose. He just saw his endo doctor who agreed with my advice and his H1AC went down too. No need to go back up to 2mg Ozempic. Hope this info helps you. Careful with new drugs. FYI: the reason Ozempic helps many lose weight is that it slows down the digestion process. Simply put: our waste sit in our intestines longer. It'd be interesting to see what a GI doctor would feel about this since it is know that wastes, particularly meat sitting in our intestines, our colon is not a good thing. I am not a physician but I have extensive experience with the medical profession and research.

barbara55109 profile image
barbara55109 in reply to FelineFandom146

All known side effects are on the label.

I have no colon.

No poop sits in my remaining, short small intestine.

I have CKD from dehydration BECAUSE of having a high output ileostomy. Most of what I drink doesn't stay in my system long enough to make it to my kidneys.

Glp drugs have several mechanisms, it is NOT as simple as slowing down digestion. I am 100% off insulin and have a 5.2 a1c from MJ.

I have been busy dying since age 15. I lost my colon at 30. I'm now 61. I've had 6 abdominal surgeries and 2 knee surgeries. I have spent MONTHS at a time in hospitals. I know more about my conditions than most doctors I encounter. Every new Dr asks if I am a medical professional. Nope, I've just read, learned and experienced so much over my 46 years of chronic illness.

honeybug profile image
honeybug in reply to barbara55109

♥️🙏❤️‍🩹🌿🌹

Badger2024 profile image
Badger2024 in reply to FelineFandom146

🥱

Benjamin124 profile image
Benjamin124

Hey, I noticed your recent post! How are you feeling now? It's a good idea to talk to your doctors about your concerns. They can give you clarity and address any worries you have about your medication.

S_dillow profile image
S_dillow in reply to Benjamin124

ivve got sharp pain on both sudes now going to my back and my pcp never got back to me.gonna try again monday.

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