Severe fatigue from stage 4 PKD, 16% gfr has finally struck, actually I just had my blood drawn again but don't have the numbers yet. Exhaustion has set in. All I want to do is sleep, but life has to go on, work etc. I just wanted to hear about others experience as I have managed well until now, it was a downhill spiral after that strenuous business trip I took last month. I honestly cannot believe I can feel this awful day after day. My blessings and thoughts and prayers to all of you who are suffering through any type of problems from CKD/PKD. The doc's don't seem to acknowledge the relation to the disease even though it is documented. I am just told that I will feel better once I start dialysis, and that doesn't really help. I am looking for reassurance that it is O.K. to slow down and rest if I need to, because I am just not use to this.