Has anyone felt leg or thigh pain or soreness after first dose of ocrevus?

[mm1527mm]

Had slight flushing and tickle in throat very short while during infusion which lasted only a brief time. At night feeling leg and thigh pain/soreness. Has this happened to anyone?

[rjoneslaw]

I haven't

[Iona60]

I'm guessing that you received IV steroids (solumedrol) prior to your Ocrevus infusion. This often gives a weird metallic taste in the mouth. The leg pain could just be from MS.

[rjoneslaw in reply to Iona60]

b4 O I had severe spasms in my right leg after my 1st half the muscle relaxed

[mm1527mm in reply to rjoneslaw]

Thats good to hear. I hope it helps

[mm1527mm in reply to Iona60]

Yes i did have the solumedrol. Luckily no weird taste in mouth although i did have a weird taste when i had prendisone when hospitalized in july. The leg pain is strange because i never had this kind of leg pain and i read some people felt worse and trouble walking after Ocrevus. Hoping this is not the case

[rjoneslaw in reply to mm1527mm]

I was told when you get IV infusions eat a piece of hard candy to get rid of the taste

[Juliew19673]

No I have not, just the usual dry/scratchy throat during actual infusion, that goes away.

[Juleigh21]

I didn’t.

[mm1527mm]

Thanks all, i actually called the dr and he said it was not related. Took tylenol and it went away

[pamgarner]

I had sore throat during infusion but no leg pain

[mm1527mm in reply to pamgarner]

Thank you. I let the dr know and he told me he did not think it had anything to do with the infusion

[kdali]

I had hip pain during the first half dose.

[mm1527mm in reply to kdali]

Oh wow. I did not know if the pain was from sitting all day. I asked the dr he told me that he did not believe it was from the infusion. I took extra strength tylenol and it went away luckily

[kdali in reply to mm1527mm]

I think mine was the IV steroids because it didn’t last long. Maybe it was the weird recliner too, but I was up peeing a lot.

My horrible headache was the steroid for sure. I’m just thankful I wasn’t grumpy too 🤣 The second infusion was fine and I went out with the family right afterwards and did a 2mi walk around the lake before dinner.

[mm1527mm in reply to kdali]

Im thinking it was the steroid also because i was fine the next morning and now that i think of it i remember feeling that way when i was hospitalized for my first flare up

[jorrell]

The leg pain is fairly normal and short lived (this is my experience talking) after steroids if you also take something like Zocor. For me, the leg muscle pain lasts for about 2 days. It feels like I just ran a 30 mile marathon alone with a bear chasing me.

[mm1527mm in reply to jorrell]

Funny that’s exactly how i felt and i was like i hardly moved that day because of the infusion.