I have a major decision to make soon. I currently take Tysabri (last 10 years) and was asked about switching to Gilenya. I'm pretty comfortable with Tysabri and haven't had any relapses in many years but because of the threat of PML and since it has been 10 years, is it time to switch. I have a negative JC VIRUS now, so that's not an issue. I'm currently reading over the literature now and I'm leaning towards switching but I'm still undecided. Anyone taking Gilenya and how do you feel?