First peg dose

[Bobadog]

Hi,

I took my first Peg dose 6days ago.

I still feel,fatigue+,mild flu like symptoms.

I’m on 45mcg every other week.

I sure this will settle soon. Do these symptoms subside with repeated injections?

How many weeks does this usually take?

Thanks Bobbie

[Jynx93]

Hi,I’m ET Jak2. I’ve had Peg for 4 months now at 45mcg weekly. I still have bad fatigue and it doesn’t seem to get any better. That’s the only symptom I have and I can live with that as some people get very nasty effects so I consider myself very lucky. Everyone is different and reacts to it differently so I can only tell you my experience. You seem to be on a really low staring dose, maybe things will change as you get further along your MPN journey.

Good luck with Peg and I hope it’s very successful for you.

[Bobadog in reply to Jynx93]

Thankyou for sharing your experience.I can live with these symptoms at the moment too,with paracetamol etc.

I will adapt my life accordingly.

The plan is to increase the dose after 3 months ,if the bloods are ok,

Good luck with your treatment ,

[hunter5582]

I am at 45mcg PEG for PV treatment. Started back in May. So far I have not had any side effects. I had the fatigue from iron deficiency before starting the PEG. It is part of why I started it. It seems my energy levels are starting to improve after about 5 months. I expect it has to do with my iron levels creeping up as the PEG is controlling the erythrocytosis. We are all different in how we react.

Some people do find that the PEG side effects diminish as their body adjusts. You are on a very low dose. Hopefully you will find that you will tolerate the PEG as your body gets used to it.

All the best.

[Bobadog in reply to hunter5582]

Thankyou Hunter I’m sure I will .

I look forward to swimming again very soon , when my energy returns ,even at half pace!

All the very best

[hunter5582]

There is a bit of a paradox that sometimes spending energy builds energy. Sometimes we just nee to rest and go with the flow; however, moderate exercise will actually sometimes help to combat the fatigue. Finding the right balance is the key.

I am stepping up my exercise level and looking to drop some of the COVID pounds I gained. Hope you enjoy your swimming.

[Bobadog in reply to hunter5582]

Many thanks Hunter Finding the right balance will be an ongoing challenge for me,as I’m sure it is for others here.

I hope your exercise regime goes well.

[EPguy]

You might ask your Dr about N-AC if your effects don't get better. See

healthunlocked.com/mpnvoice...

In the post from "fee13" N-AC was helpful. But you should discuss with your Dr.

[Bobadog in reply to EPguy]

Thankyou for this interesting post.It’s great to know there is some ‘antidote out here for side effects ,that may work.It is really helpful and encouraging to share this,

Thankyou

[EPguy in reply to Bobadog]

You may have seen my many refs to the post:

healthunlocked.com/mpnvoice...

It's very worth sticking it out with INF if the effects are tolerable. As others have said, INF is especially about long tern benefits.

[Threelions]

HiI’ve been on Interferon for 2yrs +. I do get fatigue in general but usually only feel under the weather for a day or 2 after injection.

I’m sure you’re already doing the following;

Inject a couple of hours before bed time .

Make sure you stay very well hydrated (essential)

You say you’re taking paracetamol which i also do.👍

All I can say is my effects from injection haven’t changed but I have got used to them. It’s a great medicine if you can tolerate it ok & I’d say that in getting used to it over a period of time makes it reasonably easy to live with.

Good luck & let us know how you get on with it in the future.

Mark

[Bobadog in reply to Threelions]

Hi Mark,Many thanks for the supportive message.

I can tolerate these symptoms presently, and hopefully manage life accordingly in future .

The flu symptoms have eased,just the .usual fatigue

I will certainly give it my best shot….no pun intended 🤪

I’ll keep you posted,

All the best with your treatment,

B