Erythropoiesis

[hunter5582]

Recently found this great presentation that explains erythropoiesis. It provides a terrific base to better understand what is going on in our bodies with PV. This presentation is relatively easy to understand, but the presenter moves really fast so be prepared to use the stop and rewind button.

youtube.com/watch?v=kcnOXlr...(Not working as expected?)

[Tess74]

I've watched a few of this chaps vids, I like his simplistic style of explaining things x

[Iwillwin123]

This is a great link . Really good to clarify the basics . Watched it twice . Thankyou for sharing it .

[hunter5582 in reply to Iwillwin123]

I had to hit the rewind button a bunch. And take notes. Watched the Hemostasis: Coagulation Cascade too. lots of rewinds. Will have to watch a few more times. That one really is complicated.

[Iwillwin123 in reply to hunter5582]

Will view those too . As you never tire of saying , awareness is the very key to informed decisions.

[Bluetop]

Phew! Thanks for posting -I love the way he keeps saying 'it's so simple' -but it does put a lot of things in perspective for me and I will certainly need to watch a few times. Thanks

[JT_Marlin]

Very educational! So if hypoxia is one cause of excess production of RBCs due to the EPO signal instructing bone marrow stem cell to turn into one, is it reasonable to assume that intense (oxygen depleting) exercise for anyone but especially for PV patients could be a risk factor to shorter term overproduction and possible clot formation?

[hunter5582 in reply to JT_Marlin]

I have never heard that intense exercise would have that impact. When exercising intensely you also take in a lot more oxygen. Perhaps one of our more knowledgeable scientists could weigh in an that. What is most certainly true is that extended periods of exposure to high altitude does increase erythropoiesis. So does smoking. Anything that induces hypoxia will increase erithropoiesis.

[JT_Marlin in reply to hunter5582]

Yeah that is a good point. I had a heart attack and stroke, and both happen to come some time later after intense exercise. In fact most of my visual aura migraines come after this exercise too. I am convinced there is a connection.

[hunter5582 in reply to JT_Marlin]

Watch the presentation on Hemostasis: Coagulation Cascade if you get a chance. You might find some useful information there.

[Alex9621]

Good information!! It really shows how everything is connected and what we put in our bodies is important. May explain things I didn't know before to.

[Buggerbear]

Wow,,,,,had no idea of all the steps involved in making RBC!! This video really explains it in detail and I also had to stop and back up many times, Thank you for sharing Hunter and will definitely save these.