Platelets!

[Bluetop]

I have PV and have been on hydroxy for 3 years and this has been controlling my bloods. However, after research here and elsewhere I decided to see if my diet could help. I have been on an anti inflammatory diet for about 12 months and have also included regular curcumin. For 3 successive blood tests my platelet levels decreased and my hydroxy dose was gradually reduced. This week my platelets have more than doubled to 697. The only thing I have done differently is that I forgot my tablets when I went away for a weekend 3 weeks ago so missed 2 tablets, but took a double dose when I got home (so 1 tablet less in total). I also took the opportunity to switch to taking my hydroxy and asprin at night instead of morning.

Has anyone else had a sudden platelet increase like this? (All other bloods fine) any suggestions?

[Applesnpears]

Platelet levels can vary over time due to other illness/infections. Different laboratories and analytical techniques can also produce different results. A single unusual result does not necessarily mean there has been a change in your PV. That said it would be worth speaking to your haematologist about getting another test done.

[Bluetop in reply to Applesnpears]

Thanks. Yes, I was thinking I would ask for another test -it was just so out of synch with the pattern I have had over 3 years.

[hunter5582]

Hard to say based on a single read. Could be a case of reactive thrombocytosis or even just a random fluctuation as out levels can rise and fall periodically. Hope you next lab is more reassuring.

[Bluetop in reply to hunter5582]

Thanks. I am not aware of anything which could have caused it, but I will ask for a second test -I dont feel comfortable just doubling up the hydroxy again and waiting another 3 months. As you say, there could be another cause.

[hunter5582 in reply to Bluetop]

Makes sense to get another lab done. Don't double up doses on HU. it is a toxic med and you do not want to create more problems than you solve. Here is the missed dose instruction from ePocrates.

What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Hope your next read is better.

[Bluetop in reply to hunter5582]

Thanks for that. Getting to speak to the haem not easy at this time of year!