Kidney infection and jakafi

[Cja1956]

Hello, all,

So this past weekend I went to the emergency room because of severe lower back pain. It came on suddenly two nights before but I was in agony Saturday night. It turned out I had a UTI which had traveled to my kidney. I read on line that UTIs are one of the side effects of jakafi. Has anyone else ever experienced this?. I’m not taking any other medication right now for my PV.

Thanks in advance for any thoughts you may have.

[Osteomyelio]

I got a UTI on Jakafi, so my hematologist placed me on Suppressive Antibiotic Therapy.

[Cja1956 in reply to Osteomyelio]

I’m not sure what you mean by suppressive immunotherapy but at the hospital they gave me dilautid for the pain, IV antibiotics and sent me home with antibiotic pills to take.

[socrates_8]

Hey Cja...

Yes, is the short answer. Ruxolitinib, is an immunosuppressive medication that causes our immune systems to become lowered, in the hope of stemming the over-abundance of stem cell/blood cell proliferation.

Unfortunately, for us, that also implies that we might be at far greater risk of attracting other serious infections...

Including, Urinary Tract Infections, (UTIs).

Hence, if we are to remain happy, fit and healthy... We must now take far greater precautions in avoiding potential infections, in my view...

There are many basic ways to achieve that like hand-washing, wearing a mask in winter in public places, and being very careful around our little germ'y grandchildren, when they too have some type of infection or other etc... Me personally, I bump fists today rather than shake hands... My grandson taught me that one...

It seems to be a little known or discussed fact that many more people with an MPN, will more likely succumb to either infection, brain/heart strokes rather than that much smaller percentage, who actually fall directly to their MPN...

Food for thought hey... (?)

Best wishes

Steven

(Sydney)

[Cja1956 in reply to socrates_8]

Thanks, Steven, for your thoughtful reply and your good advice, as usual. After 11 years with this disease, I am still learning. All the best,

Cindy

[socrates_8 in reply to Cja1956]

So are we all Cja... Hopefully... ;-0)

[mhos61]

My hubby is currently going through similar. He’s on a Jak inhibitor (baricitinib) for RA. Today he has just been prescribed a fourth course of antibiotics to try and combat a stubborn UTI. Hope this one works, antibiotic resistance is worrying.

[Cja1956 in reply to mhos61]

Interesting you mentioned that. My partner sent me an article from the New York Times yesterday specifically targeting UTIs as resistant to antibiotics. I hope your husband finds something to help him soon.

[mhos61 in reply to Cja1956]

I actually read that article whilst googling! Yes, hope these work. Hope you remain well on the Jakafi too. Xx😊

[Cja1956 in reply to mhos61]

Thanks.

[Lifam]

I am not taking the same medicine, I have been on HU, but I do wear mask in public places especially shopping in supermarkets, also it's winter over here in Australia, lots of people having virus and coughing. It really pay to protect ourselves from infections wherever we could.

[Cja1956 in reply to Lifam]

I was on hu and jakafi up until about 6 weeks ago. My doctor took me off the hu at that time because of anemia. I never thought about wearing a mask. Maybe that will be something I do in the future.