Have just read the possible side effects of Hydroxy - loss of appetite,weight loss, constipation, confusion, mobility weakness - all of which I have - also every drug I have been given have caused horrendous side effects. Spoke to haemo. Dept. Today and learned that my bloods "are fine". She had no answers re the above. I wonder if any others have similar problems. In essence, she said it was up to me whether I took Hydroxy. Or not - am on the same dose now -2000mg 6 days and 3000 one day and have been on this dose since diagnosis 4 years ago. I said it seems to me that they are only interested in blood results and not the person. Have any of my MPN friends had similar problems? Thank you in advance. Mary.