Hi. Live in US. Am 64, diagnosed almost 2 yrs ago w/ ET & JAK2 positive. Just started Hydroxy 2 weeks ago after more blood clots discovered. New doc says also hVe MF. Starting HU makes this all more real. Am very concerned about Hydroxy, side effects & risk of causing leukemia. Also concerned at risk of progression into full blown MF. Already have a rare immune deficiency so reduced immune function of HU concerns me. Reading all your posts on this forum has helped me feel less alone. Thanks. Sorry if I sound down.