Doses over the years. Told I had changed to MF only in November last year that was such a shock.Taken of Hydrox completely 4 weeks ago only take asprin at the moment. Due to anaemia sweats &fatigue & an enlarged spleen..its all happened so quickly. I feel they sew the seed to make you think talk to your family etc. I am still in deep shock. Has any one had the same thing happen to them. Also talk of perhaps taking the new drug Ruxolitinib.