Treatment options?

[kellyOd]

Has anyone been in a place where the doctors say no immunotherapy or targeted therapy? Is there anything else to try?

I am willing to hear anything..

[missyrand Ambassador]

Chemotherapy with cysplatin and taxol combo, with which I think you are familiar. Radiation to large tumors for palliative relief. Cyber knife for large tumors, again this is a palliative strategy

Peace to you Kelly and Ryan

Missy

[missyrand Ambassador]

Kelly, another resource to look at is a relatively new law passed in 2018 called the Right to Try, but you have to have exhausted all standard treatment and be ineligible for a clinical trial first: fda.gov/patients/learn-abou...

Missy

[missyrand Ambassador in reply to missyrand]

Kelly:

Here are some other trials to see if they might fit for Ryan:

Other avenues to consider are related to use of varied types of Interleukin:

Aldesleukin (Interleukin-12)

oncosec.com/tavo/ This trial is using tumoral injections with electrical pulses to try to create abscopal effect (make one tumor active and it will teach the rest of the body) and targets non-responders to PD1 therapy. NCT03132675 at St. Lukes University Health Network in Bethlehem, PA Call 484.503.4152

or

Aldesleukin (Interleukin-2) used in combo with Pembro at Rutgers NCT02748564. Principal Investigator is [e-mail]

Completing forms on the Melanoma Research Foundation and Melanoma Research Alliance websites will get a printout from a navigator looking at clinical trials relevant to your individual situation. We used it about 2 weeks ago.

Peace,

Missy

[SGHSweethearts]

Kelly,

I wish I had some answers for you. All I can offer is my prayers for you and Ryan.🙏🏻

Michele

[HSsweetheart]

Yes, my prayers are with you and Ryan