Mycophenolate and pregnancy : To the ladies taking... - LUPUS UK

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Mycophenolate and pregnancy

Tash1987 profile image
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To the ladies taking mycophenolate, does this medication make it harder to become pregnant

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Tash1987
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baba profile image
baba

Please see:

bnf.nice.org.uk/drug/mycoph...

"Conception and contraception

Pregnancy prevention

The MHRA advises to exclude pregnancy in females of child-bearing potential before treatment—2 pregnancy tests 8–10 days apart are recommended. Women should use at least 1 method of effective contraception before and during treatment, and for 6 weeks after discontinuation—2 methods of effective contraception are preferred. Male patients or their female partner should use effective contraception during treatment and for 90 days after discontinuation.

Pregnancy

Avoid unless no suitable alternative—congenital malformations and spontaneous abortions reported.

Breast feeding

Manufacturer advises avoid—present in milk in animal studies."

Paul_Howard profile image
Paul_HowardPartnerLUPUS UK

Hi Tash1987 ,

Mycophenolate mofetil is linked to congenital abnormalities and therefore should be stopped and changed to an alternative (such as hydroxychloroquine and/or azathioprine) about three months prior to conception. This should be done carefully under your doctor's supervision.

I am not aware of this treatment affecting fertility in any way, so taking it should not make it more difficult to conceive in the long run.

If you need more information about lupus and pregnancy, please take a look at our booklet here - lupusuk.org.uk/wp-content/u...

I can also send you a copy of this booklet in the post if you would like? Just send me a private message or email paul@lupusuk.org.uk with your name and address.

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