Naproxen

[Kai153]

Does being on 500mg naproxen twice a day reduce your esr or crp levels?

[PMRpro]

It can do yes. Naproxen is a NonSteroidal AntiInflammatory Drug (NSAID) and can reduce the ESR a fair bit - but it seems to have no effect on CRP.

That was the result of a study in patients with a vasculitis called giant cell arteritis.

ncbi.nlm.nih.gov/pubmed/213...

[Barnclown in reply to PMRpro]

Are other prescription NSAIDs proven to reduce ESR &/or CRP?

[PMRpro in reply to Barnclown]

I think most NSAIDs will reduce the ESR (so do statins):

ncbi.nlm.nih.gov/pubmed/213...

but the CRP is a bit different:

ncbi.nlm.nih.gov/pubmed/228...

where they found they didn't do anything overall - but naproxen reduces the level and one of the cox-2 inhibitors RAISES it (is that how the heart effect is modulated?)

[Barnclown in reply to PMRpro]

👍👍👍👍 thanks 😘