All, would appreciate your feedback on the following please. I invested in the Roche CoaguChek XS machine and use it regulalry to monitor my INR. Last week I had my INR tested in the clininc I go to weekly and the reading came back at 2.2. I used my CoaguChek machine while in the clinic and its reading was 2.6. Yesterday, my clinical test came back at 3.6 while my CoaguChek machine read 3.4. Have any of experienced this degree of variation? This is important for me because I travel long-haul a great deal, and if my INR is below a certain level I am supposed to inject Clexane pre-flight. A scary thought if my CoaguChek is giving me incorrect readings. Thanks.