IgG levels

[Lauriem4]

Just been diagnosed and a bit confused. Would anyone mind sharing their igG levels with me? Thanks

[Lure2]

Welcome!

I wonder about your diagnose of APS; did you see a Specialist of autoimmun illnesses and did he or she take the usual 3 antibodies twice with 12 weeks between the bloods taken.

How many of them were positive ? To have a diagnose we also need some sort of special symptoms typical for our illness. Which did you have?

The levels of the IgG are not so important. Did you also have IgM taken? The levels may go up and down.

Did you get some drugs for your APS?

Stay with us here. Several knowledable members may be able to help you with info. Also try to read as much as possible about this rare illness as so few Doctors know about it. Very important to get a Specialist who is working daily with people like us to get a correct diagnose and also a helping drug. We have too thick blood that has to be thinned at a rather high INR-level sometimes if we use Warfarin which has been my lifesaver.

[Lauriem4 in reply to Lure2]

Hi thanks for your reply . I've been diagnosed after having 2 late miscarriages and the letter only mentioned igG being 60 I shall have to contact them for more information. Thankyou

[Lure2 in reply to Lauriem4]

Important with a Specialist as I said and take the 3 autoantibodies like I said above twice with 12 weeks between she bloods taken. Ask for a copy of the bloods taken.

[Lauriem4 in reply to Lure2]

Yes I will do thanks for your help x

[Lure2 in reply to Lure2]

The 3 autoantibodies should be; Kardiolipinantibodies, Beta-2-Glycoprotein1 and also Lupus Anticoagulant

[hihannula in reply to Lure2]

Hi Lure2. Just curious. Have you developed arterial calcification from all the years you’ve been on warfarin?

[Lure2 in reply to hihannula]

Hi hihannula,

I have no idea. Warfarin has been my lifesaver. I take Calcium and D-vitamin ever day on prescription.

[Lure2]

As to myself; I have all three positive and very high titres all the time (>160) both IgG and IgM (the IgM a bit lower). I think that you do not have all three antibodies positive as you have had 2 late miscarriages. Do not worry just get a correct Diagnose as that can be difficult to get without the Specialist you need.

[Lauriem4 in reply to Lure2]

Yes I had excessive clotting in the placenta. Yes maybe just one was positive then I will find out . Thankyou

[GinaD]

IgGs, IgAs and IgMs are markers of autoimmune antibody activities and types. Given the nature of our day to day lives, these numbers fluctuate depending on what virus or bacteria you inhaled on the bus after that person sneezed in your direction, or what kind and how much pollen is in the air today, or whether or not you are eating a food you are allergic to. This is why the road to an APS diagnosis is usually guided by positive test results at least 6 weeks apart. I had sky high IgG numbers as well as moderately high IgAs and IgMs until I finally realized a gluten allergy and went on a gluten free diet. I do have APS --or, as some docs insist, I HAD a clear case of APS but since going gluten free all my blood work is now, as one hematologist said, " boring." Yet I stay on warfarin with a very low INR as science is still a bit conflicted on the issue of whether or not a dietary change can " cure" APS. So... high IgG marker is an indication that further tests should be done. Were they?

[SteveRN]

Hi Lauriem4First of all let me say how sorry I am to hear about your losses during your pregnancies, your specialist would have looked at the obstetric criteria I.e. the clots that you had in your placenta and taken your antibodies you mention your IGG but I suspect that you had others taken as the criteria in pregnancy is the same as in any other case and requires more than just one. So as other people have suggested go back to your physicians and ask for your results but perhaps ask them to explain what the plan is for the future. You are not alone there is plenty of advice on the forum and there are other mums who have also had multiple losses during pregnancy but that have also subsequently gone on to have successful ones. It is a lotto take onboard when you are faced with a new diagnosis it takes a while to understand it. Good luck there are lots of us here to support you.

Kind regards

Steve

[Lauriem4 in reply to SteveRN]

Hi thanks so much for your reply . Yes there is a much better chance of a successful pregnancy with the blood thinners so fingers crossed and thanks for the kinds words, I will find out more about the condition.

[SteveRN]

Hi There are a couple of books that you may find useful there is “Understanding Hughes Syndrome”case studies for patients written by Prof Graham R.V. Hughes and “Sticky Blood Explained” Antiphospholipid Syndrome by Kay Thackray. I bought these a while ago I think I got them on Amazon. Hope this helps.

Kind regards

Steve RN

[Thick_Blood]

Mine are constantly low.

Immunoglobulin G subclasses