APS and menstruation

Hi everyone, hope you're all well?

I'll try to spare details as all you ladies will be only too aware of the effect of anticoagulation and periods; I started on warfarin but am now on Acenecoumarol, (and many others), target INR 3-4. my periods have stopped! I know I'm not pregnant and I am not menopausal. I am 37yrs old.

I will talk to my Dr, but has this happened to anybody else? I am wondering if it could be medications, or (more likely) ? general poor health.

Has this happened to anybody else?


Annie x

9 Replies

  • Hi there, it may be a temporary reaction to starting new drug, but I certainly would ask GP/Clinic Nurse/Consultant etc, as I am sure others on similar drug combinations will have asked these questions. Sorry to not be able to help with more detail! Mary F x

  • Hi Mary,

    Thank you so much for your reply. I know it's not an easy one to answer, but I always get sensible advice from this site. I have recently started carbamazepine in addition to the whole cocktail, so it is hard to decipher what causes what, but it makes sense to think it could be the new drug... I will talk to one of my Dr's... but which one? Ha!



  • When I started on warfarin I had a heavy bleed for 2 weeks. It only stopped when I stopped taking the warfarin. (Not recommended though).

    Now my periods seem to have stopped but it may be linked to age and menopause.

    Maybe this needs a different thread, but I was wondering whether ladies suffered painful periods prior to anti coagulation. For most of my life I had a dreadful time when all other things seemed okay. The pains would cause everything else to stop.

  • My periods were so bad. . . ( in my own ears this sounds like the first line from a comedy routine ) . . .

    -- that I frequently ended up in the ER month after month when I was in college.

    I had 1 hour after I spotted. 1hour! To get myself to my room or other " safe" spot where I found crawl to a bathroom and remain prone for 12 hours. Once I was taking a final and was so intent on my essay I didn't notice the warning twinge. I passed out as I was handing my completed test to my prof. The ambulance was called and off to the ER I went.

    Other times well meaning room or hall mates would see me crawling to or from the bathroom and would ignore my protestations that I'd be fine by the next day and would again, call the ambulance and off I 'd go.

    At my University's ER the docs experimented giving me this or that drug when I was drug in. Finally, in 1978 I found myself back home in West Virginia in the care of a new ( to me) OB/GYN who wrote me a script for a new NSAID / anti-prostaglandin called" naprosyn.". A miracle! My periods hurt, but I did not pass out. I could walk! I could talk! I could even get through my shift as a clerk at the book store!

    I have often wondered if this has any connection to the Hughes Syndrome.


    There was precedent for my horrible periods. This was fairly common in my Grandmother's mainly Irish family. As my Great-Aunts predicted, all this went away and I no longer needed the naprosyn after my first child was born.


  • All that sounds so familiar I could have written it myself. Many times my periods were so severe with pain I used to lose control of my bowel. I had absolutely no alternative than to stay confined close to a bathroom. Other times the only relief used to come from me directing a hot shower spray at my abdomen for hours at a time.

    Like you, regularly the symptoms would resolve by the next day.

    ...And now Hughes. Well I wonder as well.

  • Hi, my periods were very heavy when I started anti-coagulation, which is why I am surprised they have stopped...

  • Im on aspirin, im 51, my periods have been awful since im 13. Come on menopause

  • I am 51 and up to taking warfarin had very easy problem free periods.

    Once on warfarin they became heavier and more painful, by my standards anyway. This has progressed but with age I know I have expect odd things happening as I approach menopause, or maybe I am in it now.

    Right now I cannot say when they will come, when they will stop or hi heavy they will be, makes life a bit complicated I can tell you.

  • Are you underweight?

    Periods can stop if you are underweight.

    Also you are at that age where they can start to be irregular.

    Definitely make an appointment to discuss it with the GP, but not to worry.

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