“Non-celiac wheat sensitivity: rationality and irrationality of a gluten-free diet in individuals affected with non-celiac disease: a review”
bmcgastroenterol.biomedcent...
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The above is a review article about the complications and clinical aspects of a diagnosis relating to Coeliac Disease and non-Coeliac Wheat Sensitivity (NCWS).
The research community is still working on figuring out a clear way to diagnose NCWS.
As the above article shows there are ways to define based on gut biopsy findings. Diagnosing Coeliac Disease in itself is by intestinal biopsy as the standard sets out. But this can be complicated and takes skill of the physician as there are overlapping findings between different gastrointestinal conditions. For instance the increase in intraepithial lymphocytosis is seen in not just Coeliac but quite a few other disorders too.
Anyway this may be of interest to all the ‘gluten intolerant’ out there, especially if you like the science. 🙂