Repurposing: antipsychotic drugs for cancer

[Maxone73]

Or maybe they won't help with it, but we would not care! 😜😜

Repurposing antipsychotic drugs offers a promising, cost-effective approach to cancer treatment. These medications, already tested for safety, could move swiftly into clinical trials and potentially enhance current therapies.

First-generation antipsychotics like haloperidol and trifluoperazine, as well as second-generation drugs like olanzapine, have shown anti-cancer effects, such as inducing cell death, halting tumor growth, and boosting the efficacy of chemotherapy agents.

While side effects and limited clinical trials remain challenges, the pre-clinical data suggest that with further research, these drugs might provide new treatment options for various cancer types.

prostatewarriors.com/2025/0...

[Seasid]

Thanks, I am really fine.

[pd63]

I'll consider it I start hearing voices

[JohnInTheMiddle]

I still have an unused bottle of olanzapine, which I was given prior to my successful cycle of six Docetaxel chemo infusions. The reason for this was rather vague and something to do with making the chemo more tolerable. Seemed kind of strange. Is it possible that the prescribing doctor knew about it off label capabilities and was trying to help?

[Maxone73 in reply to JohnInTheMiddle]

Good question!

[Seasid in reply to JohnInTheMiddle]

Believe me it has nothing to do with the drug off label capabilities, it would be too much to expect from our doctors in general.

[Seasid in reply to Seasid]

"Olanzapine, sold under the brand name Zyprexa among others, is an atypical antipsychotic primarily used to treat schizophrenia and bipolar disorder.[13] It is also sometimes used off-label for treatment of chemotherapy-induced nausea and vomiting[14] and as an appetite stimulant.[15] " Wikipedia

[JohnInTheMiddle in reply to Seasid]

Exactly, that was what they told me, now I remember. They were suggesting it would help avoid chemo-induced nausea. Fortunately I didn't have anything like that so I didn't take any. I was sort of entertained that when I found out about the drug itself that it was an antipsychotic. My wife suggested that it's still might be good to try!?😂

[Seasid in reply to JohnInTheMiddle]

The drug is very toxic. It is not a lolli. I would not try it.

[Seasid in reply to Seasid]

They also gave me something against nausea and vomiting but I never needed it. Maybe some people have psychologically induced nausea just by thinking about chemotherapy and that is what this very toxic drug supposed to prevent.