Merry Christmas from space

[Maxone73]

Because science is running! I hope fast enough! Orbital Oncology....issnationallab.org/upward/o...

[Rolphs]

Fascinating and inspiring story about scientific discovery. We’ll keep our fingers crossed and see if what’s learned in space leads to clinical breakthroughs in prostrate cancer treatment.

Saluti!

[Maxone73 in reply to Rolphs]

Saluti!!

[Steel67]

Interesting!

I’ve been meaning to ask you, you’ve done such great work in consolidating much of the most relevant treatment developments, what would you consider the 2-3 most promising developments this year? Do you think we could have another breakthrough treatment available commercially in the next couple of years?

[Maxone73 in reply to Steel67]

Most promising....I must say that progress is enormous in every attack angle that we can imagine to tackle prostate cancer....let's say I am not worried about IFs but about when. With today's precision, we must find a way to speed up trials, they are the real bottlenecks. In general, I would keep an eye on delivery systems and on everything CRISPR. For the next 2-3 years I have high hopes for 67CU-SAR-BISPSMA and AMG 509. I check them often to get any news. Also ARX 517 and JANX007 are very promising but still early stage.

[petabyte in reply to Maxone73]

This is indeed an impressive result for the first patient treated with Cu67. claritypharmaceuticals.com/...

You probably posted this before but this is the first time I have seen this case report.

[Fonske in reply to petabyte]

Very promising indeed. I'm hoping it could become a treatment while still being hormone-sensitive (wishful thinking? ...maybe not😀).

[Maxone73 in reply to petabyte]

Honestly, even being skeptical when I first read of 67Cu and their results with the first patient dosed with two doses I was going to fall from my chair....but I think the fact is this, he had an exceptionally 64Cu traceable disease (64Cu is the one used only for imaging), which led to an exceptional response to 67Cu. They would have been even too lucky otherwise! But hey, I hope 99.99999% of patients have the same results (that 0.00001% are those with a wrong diagnosis of cancer!)

[petabyte in reply to Maxone73]

Maybe one day it will be Cu67/ or RP as first line treatment and radiation machines will be relegated to heating lunch for the staff.

[Maxone73 in reply to petabyte]

By the way, they have also 64Cu-SAR-BBN and 67CU SAR-BBN, SAR-Bombesin ligand for those prostate cancers with low or no PSMA expression

[MrG68]

Well actually, it will be running faster. Time will run faster due to relativity. Clocks in satellites have to be adjusted to compensate for this.