Preclinical (but quite important it seems!): how androgen receptor protein works

[Maxone73]

Scientists at Weill Cornell have uncovered how prostate cancer hijacks the normal function of the androgen receptor protein to fuel its growth.

This protein usually acts as both a growth accelerator and a brake in healthy prostate cells. However, in cancer cells, the brake function is suppressed, leading to uncontrolled cell multiplication.

Researchers discovered a set of genes that, when activated by the androgen receptor, can stop the growth of prostate cancer cells, but not healthy ones.

This finding could lead to new diagnostic tests to predict patient outcomes and guide treatment. It also opens up the possibility of developing therapies that reactivate the growth-suppressing function of the androgen receptor to halt cancer progression.

prostatewarriors.com/2024/1...

[KocoPr]

That’s all fine and dandy but WHY did they not tell us what the family of genes are that stops the prostate cancer growth? That chaps my hide!

Looking deeper into Weill Cornelss research papers may reveal the genes EZH2 and or USP11 with c-MYC

news.cornell.edu/stories/20...

vivo.weill.cornell.edu/disp...

[Maxone73 in reply to KocoPr]

I think you can access their data

[KocoPr in reply to Maxone73]

ChatGPT sent me to his lab and my browser warmed me the site could be malicious. I will look further

[Xavier10 in reply to KocoPr]

So is that like a mutation? Such that we can find a test offered online that tests for this, like color does for mutations? This seems to be a pretty important discovery.

[KocoPr]

you can certainly search these bio markers for PCa and you should see many articles on them especially c-MYC which is biomarkers and a protein that is over expressed in PCa and is cause by MYC oncogene.