The Strengths and Weaknesses of BAT, ... - Fight Prostate Ca...

Fight Prostate Cancer

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The Strengths and Weaknesses of BAT, interesting article

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researchgate.net/publicatio...

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Farmhand
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cesanon profile image
cesanon

"Abstract

It has been shown that when the amount of intracellular androgen receptor in prostate cancer is greatly amplified, such as in the cell line LNCaP 104-R2, then testosterone will stop the growth of those cancer cells. This is the principle behind bipolar androgen therapy, which alternates amplifying intracellular androgen receptors by using very low levels of testosterone with supraphysiologic levels of testosterone. This approach has achieved some limited success in human patients. However, as these cycles continue, some mutations are expected to arise that give the cancer cells a selective growth advantage and lessen the effectiveness of bipolar androgen therapy."

That all makes sense.

Ramp7 profile image
Ramp7

Now if one considers the absolute numerical value of the peaks of the cycles (very low T), cycle length, and throw in a dose of Adaptive Therapy. The outcomes may be more to ones advantage.

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