3rd transfer failed

[MiniCeeCee]

Another low fertility day today as found out this morning that our 3rd transfer failed. Hope is dwindling 😔 We’ve had two egg collections so far - first NHS one we got 4 embryos and have transferred 2 so far, 2nd egg collection was private (whilst waiting for next NHS Transfer) and only got 1 day 3 embryo which is the one that’s just failed. Private round feels like a complete waste of time, money and hope. I’m hoping it’s just a numbers game for me, and it will happen one day 🤞 just doesn’t feel like that today sadly. Any stories of hope and success after transferring multiple embryos welcome ❤️❤️❤️

[Thierry101]

sending you a huge hug. I’ve also had 3 transfers (5 embryos) fail and it’s absolutely heartbreaking. Look after yourself my lovely xxx

[MiniCeeCee in reply to Thierry101]

Thanks lovely, wishing you success too, it’s so so tough xxx

[Kittykat198]

I’m sorry to hear about your transfer. I was successful on my third egg collection, 5th transfer, 6th embryo. Fingers crossed your next transfer is your last one xx

[MiniCeeCee in reply to Kittykat198]

Thanks so much for your reply Kittykat198 , so glad to hear! Anything you did differently along the way that you could share? 🤞🤞🤞🤞 too xxx

[Kittykat198 in reply to MiniCeeCee]

I’m sorry but there isn’t a lot treatment wise. The only think that was different was they increased the progesterone after our second failed transfer. I took cq10 for our final egg collection for a bit. Even the consultant just put our final successful transfer down to luck and persistence. X

[MiniCeeCee in reply to Kittykat198]

Even this is good to hear, as helps me want to just stick with it and persevere like you say! Thanks again for sharing! xx

[CyclingAddict]

Hey MiniCeeCee, I had 4 failed transfers and 1 chemical. My 6th one stuck in and I'm now 36 weeks pregnant. You feel so hopeless when they keep failing and don't know why. I kept getting told that it was just bad luck but, prior to my successful transfer, we did do a lot of additional testing and our consultant tailored our protocol based on those results. As a couple we also started taking additional supplements.

Wishing you luck x

[MiniCeeCee in reply to CyclingAddict]

Thanks so much CyclingAddict , appreciate your note. Do you mind asking what additional testing you had? And what supplements you went on? I’m starting to wonder if I should shake up mine a little, seeing as results between egg collection 1 and 2 declined quite dramatically. Thanks again x

[CyclingAddict in reply to MiniCeeCee]

Yes, absolutely - happy to help. I did the Emma, Alice and ERA testing. 1 of them is to check your natural killer cells which can cause implantation issues (results were normal), 1 is to calculate exactly to the hour how much progesterone you should be on before transfer (it turned out they had been putting embryos back before my womb was ready and I needed an extra day of progesterone), and 1 is to check the bacterial culture in your womb (results came back that they could be improved and I was advised to take vaginal probiotics). He also ran loads of blood tests to check if I had any underlying conditions. It turned out I have hashimotos, which is a thyroid condition - a huge surprise as I had no symptoms, but usually symptoms don't reveal themselves until the condition is quite far on. He treated me for that before and after transfer as it can increase the risk of implantation failure and miscarriage. And due to the frequent implantation failure, we did PGT-A testing. He also told me to take Q10 before egg collection to improve the quality of my eggs. I started with the NHS but moved to private because I wanted him as my consultant because of how thorough he is. He did push my body to the limit when it came to egg collection, but he closely monitored me throughout to make sure it was done safely. I had 13 eggs collected during my first cycle with the NHS and, in my second cycle with him, he managed to get 21 eggs out of me (despite the fact I was 2 years older at this point).

Hope this helps x

[MiniCeeCee in reply to CyclingAddict]

So unbelievably helpful thank you! I’m due another NHS transfer next month with one of my two remaining embryos, so 🤞 for that, but in the meantime also going to prepare myself for if I did need another egg collection. So might try the vaginal probiotics and the Q10 for now. And really great to know re the other tests too - something for me to explore. Sorry for all the qns, but can I ask where you got you Q10 and probiotics from? Bit of a minefield out there when it comes to this stuff so not sure where to start! X

[Lemons1986 in reply to CyclingAddict]

Hi would you mind sharing your clinic by message?

[CyclingAddict in reply to Lemons1986]

DM'd you

[MiniMe23]

Sending you a huge virtual hug 💖

I’m so sorry that it’s not worked out this time. But please don’t loose hope. I had multiple fails. And held very little hope on my last transfer. Especially as the embryologist selected the poorer of my 2 remaining on my last transfer.

It felt like a waste of time. But that was the one that stuck around. So I truly believe it will happen for you. Look after yourself and be kind to yourself xx

[MiniCeeCee in reply to MiniMe23]

Thanks so much MiniMe23 The hope is a bit harder to cling on to each time, but messages like yours really help so thank you, and so glad you saw success ❤️ xx

[Doodlebug23]

10 embryos over 7 transfers to get my miracle BFP! Clinic always said no issues it’s a numbers game. It’s bloody hard but keep going it’s worth it!

[MiniCeeCee in reply to Doodlebug23]

So much hope in this message ❤️ thank you!! having never seen a BFP it feels so far away / impossible but these messages keep me going xxx

[Doodlebug23 in reply to MiniCeeCee]

There is hope I promise! And I totally understand how you are feeling right now cause I have been there! I had a vvv faint positive transfer 3 which turned out to be a chemical, but this BFP almost knocked me off my feet!!! 🙈

[Citizenerased83]

Hi lovely, sorry to hear your news. Its crushing every time a transfer doesn't work. Be gentle on yourself. I am currently 17 weeks pregnant - transfer number 6 was the one. We'd had 2 egg collections and 2 miscarriages previously. We ended up pgta testing our embryos due to my age and a chromosomal issue.

Wishing you so much luck x

[MiniCeeCee in reply to Citizenerased83]

Thanks so much, really appreciate your reply and hearing your story! And huge congrats on your pregnancy! I’m thinking PGTA testing might be helpful if we get enough embryos next round! Xx

[Citizenerased83 in reply to MiniCeeCee]

Thanks lovely. Hopefully all will go well with this pregnancy.

Sending you lots of baby dust. Xx

[Ffion-wyn]

hi there. Firstly, i hope youre ok. And if youre not thats okay and sending a big hug.

My 3rd transfer failed yesterday. I know exactly how you feel. In a way I feel quite numb to it? Like i just expect this feeling now.

I hope youre next round works for you but just know youre not alone.

X

[MiniCeeCee in reply to Ffion-wyn]

So sorry to hear your result too, it’s so tough. I’m exactly the same, I was upset yesterday and today, but feels different this time, like you say, I just feel quite numb, feel like I should be processing it more and crying more now. But just feel strange. I’m also going through redundancy at work, and start a new job in 2 weeks, and so my head is just a bit of a mess all round. Will you go again do you think? Have you any frozen embryos? X

[Ginbaby]

It took me 3 egg collections and 5 transfers to get my 12 week old little boy 🩵. Don’t give up hope. Xx

[MiniCeeCee in reply to Ginbaby]

Incredible news, thanks for sharing and congrats! So good to have this hope, thank you! ❤️

[Hopeful_88]

Hi MiniCeeCee , i am so sorry to hear you are feeling low after your 3rd transfer failing. It is such a tough journey to go on and utterly devastating to stare at that blank pregnancy test after weeks/months of medication and preparation.

I have no success story but want to say that I am sending you all the strength and positivity and have everything crossed for your next transfer.

I am in a similar position to you, having had my 1st egg collection and transfer on the NHS, then decided to go private for the 2nd one (to speed things up a bit). I was disappointed too with the outcome of my private cycle, as so far we have only got 2 day 4 morulas on day 4 (day 5 is tomorrow, I am hoping they continue to grow, as one is low quality) out of 7 eggs fertilised. The rest of the embryos have not grown or have stopped developing (this is something I didn't experience in the NHS, as all of the 4 embryos became blastocysts). So, I totally get how you feel about being disappointed with the private cycle! I somehow thought I would have a better outcome.

Out of interest, did you do your private cycle in the UK or abroad? I have done mine in Prague, so I am wondering if the cell culture conditions are not as good here as in the UK.

Wishing you all the best and hope you are feeling a bit better as you plan for the next transfer xxx

[MiniCeeCee in reply to Hopeful_88]

Thanks so much for the reply Hopeful_88 I hope you get the day 5 results you deserve today 🤞 It’s so tough, I think I maybe rushed into my private round a little too quickly now with hindsight, and if we do another egg collection again, me and my partner will prep a lot more the 3 months beforehand. Just so at least we know we’ve done everything we can! My private round was in the U.K too, so cell culture conditions I imagine would have been the same, just must have been a bad round for us I think. Really hope future ones are better 🤞 do you still have transfers planned with the NHS? Xx

[Hopeful_88 in reply to MiniCeeCee]

Thanks so much MiniCeeCee , I got 2 blastocysts with 1 transferred and 1 frozen, so different from my last result! It's hard not to feel let down when the results are so different from previous experience, also it stings that bit more when paying privately (we also paid for the MSS chip for sperm separation add on, which falsely increased our hopes of getting more/better blasts!).

How long did you have between cycles? Did you have different protocols for each of them? I asked my clinic why the result is not as good as my previous experience, they said it could be down to different protocols and different medications (I had long protocol on NHS, then short protocol privately).

It's so hard and I hope you are doing OK xxx

[MiniCeeCee]

🤞🤞 for your transfer, rooting for you!! I’ve had 10 months between my egg collections, around 4-5 months between each of my transfers along the way. Protocol was pretty similar in each egg collection - and so feedback from clinic was a bit vague ‘each collection is different’ - haven’t been that impressed with clinic tbh so if we go again with another egg collection, think we’ll be changing clinic. Frozen NHS transfer next month so 🤞 xxx