Embryo grade changed when thawed - Fertility Network UK

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Embryo grade changed when thawed

Mar786 profile image
36 Replies

Hi all

Just after a little hope!! I had my embryo transfer today was a 3bb embryo grade before thaw but once thawed turned into a 4bc - since my transfer i cannot help but thinking i stand not chance with this grade due to C.. has anyone else had a frozen embryo that changed graded once thawed? My dreaded 2 week wait starts and i just feel so disappointed already - previously i had a chemical with a 3bc!!! Thank u xx

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Mar786 profile image
Mar786
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36 Replies
minnesota_girl profile image
minnesota_girl

I've never had the clinic tell me either way but they wouldn't have transferred it if it hasn't shown signs of growing and progression which is the most important thing!!

🤞🤞✨✨ For you 💕💕💕

Mar786 profile image
Mar786 in reply to minnesota_girl

Awwww thanks for replying!! And yes your right praying this little frosty sticks xx

Solly-44 profile image
Solly-44

Hi, yes I have had them change when thawed. One went up to a really great grade from pretty average and I got pretty excited but it didn’t stick. My son came from a lower grade transferred later so I know it’s hard but try not to get hung up on it. (Easier to say than do eh 🤪). Wishing you so much luck xx

Mar786 profile image
Mar786 in reply to Solly-44

Thank you - your experience has helped me alot will try and stay positive!!! Xxx

cloud_user profile image
cloud_user

My clinic told me this is totally normal! Did they tell you if 100% of the cell's survive and if it was expanding again post thaw?

Mar786 profile image
Mar786 in reply to cloud_user

Yes they did say it expanded very well after thaw!! I guess i just expected the grade to either stay the same or be better but we will see. Really hope it sticks!!!

cloud_user profile image
cloud_user in reply to Mar786

so after two excellent grade transferred, i just had a 3bb FET which defrosted in a similar way to yours. I almost wrote it off for the same reasons as you, seemed too poor quality. just had a 6+3 day scan, and there was a heartbeat! first time we've gotten that far

Mar786 profile image
Mar786 in reply to cloud_user

That is amazing!!! Thank you soo much for sharing Pray you continue to have a healthy pregnancy xxx🤗

Hopefulmother profile image
Hopefulmother in reply to cloud_user

This gives me so much hope. My 3AA and 3BB didn’t stick and I only have one 3BB left. I almost considered disposing it since it seemed poor . Hoping to use it in June

cloud_user profile image
cloud_user in reply to Hopefulmother

Please dont dispose of it! if its good enough to freeze, its good enough to make a baby!

Hopefulmother profile image
Hopefulmother in reply to cloud_user

This made me smile and raised my hopes. My last cycle was semi natural as we only used Femara before the transfer. This cycle they want to do a fully medicated cycle. Does this make much of a difference as my lining and bloods were great with the last one so they said I’m embryo was probably weak

Mar786 profile image
Mar786

Thank you sooo much!! You have made me feel better aready ☺️ xxxx

Fr_Traveller profile image
Fr_Traveller

I had a 4bc and a 3/4bc - transferred - and both of those were day 6 embryos that didn't seem to be getting anywhere on day 5...currently 15 weeks pregnant with one of those! It's definitely possible. Good luck! Xx

Mar786 profile image
Mar786 in reply to Fr_Traveller

Thanks soo much for your reply! Its so re-assuring xxxLots of luck with the rest of your pregnancy hope it goes smoothly!!! 🤗

KiboXX profile image
KiboXX

My clinic don’t tell you the grades. My previous clinic did and I found it caused more stress as you worry about stuff like this!

If it’s good enough to freeze and transfer, it’s good enough to make a baby ❤️ Good luck!xx

Mar786 profile image
Mar786

Thanks xx

In a way its soo much better when they dont tell you the grades -ahhhhh causes soo much anxiety but like you said it was good enough to freeze. I hope it stays strong - this 2 week wait will be tough but🤞xxx

KiboXX profile image
KiboXX in reply to Mar786

Yeah I just don’t think it’s necessary, I much prefer just being told it’s a good enough 😊

Keeping everything crossed for you xx

Mar786 profile image
Mar786 in reply to KiboXX

Yes definitely!! Thanks soo much xxx

I’ve definitely read of successful results with a 3bc and whilst you lost the b you gained a 4 which is great. Haven’t heard of it changing but they are cells so that makes sense and it’s only their state they’re in now that leads to the grading. Try not to worry about that and good luck for the 2WW

Mar786 profile image
Mar786 in reply to Positivechangeplease

Thank you so much for your reply - really needed this!!! Ahhhhh don’t know how i will get through the 2ww 🙏 xx

Positivechangeplease profile image
Positivechangeplease in reply to Mar786

I know it’s so hard. I wish you all the relaxation you can muster!!! ❤️❤️❤️

Mar786 profile image
Mar786 in reply to Positivechangeplease

Thanking you!! Whats worse is im sooo impatient and tend to do early tests!!! I will try my best not to test early☺️Xx

Positivechangeplease profile image
Positivechangeplease in reply to Mar786

I found it was better for my psyche to wait the full time. I’d talked myself into the expectation of disappointment so either way I was prepared

Mar786 profile image
Mar786

Hi ladies just a quick update - last ivf cycle i ended with a chemical pregnancy and really thought the progesterone was the culprit so this time i really pushed for blood test to check my levels - at transfer they did a bloods and today have phoned me to say my progesterone is low!! So have increased my cyclogest to double dose and i have to go in for another test on Monday and they may give me injections instead!!!!!! So so worried now..

Riri88 profile image
Riri88

Hi Mar786,

Good thing you had the progesteron checked! At least they are monitoring it now which is much better! What were your suspicions for having a progesteron issue?

I just had my transfer an hour ago, thawed well but graded 4BC and wondering the same as you of course how that will work out in chances. I had a BFN and a chemical before with better day 5 embryo’s and this is our last frostie so anxious but trying to be positive!

Seems like we are TWW buddies with same grade embryo so let’s keep everything crossed for these to proof grading isn’t important!

Mar786 profile image
Mar786 in reply to Riri88

Thank you for your lovely message!!! Yes we can be tww buddies ❤️!!

In regards to progesterone I had a very clear positive last time with a 3bc grade but started bleeding early on so i asked my consultant to make sure i have my progesterone checked this time - lucky i did as now they have picked it up. My clinic are closed over weekend so have to go in on monday.

Crossing my fingers for both of us xxx

Riri88 profile image
Riri88 in reply to Mar786

Aha yes with bleeding that is definitely something to get checked! Let’s hope the extra dose of progesteron should help and double checking on Monday if you need even more!

You would think they would offer this themselves but I have found you sometimes need to push for things. So well done on that!

Wishing you a good start of the weekend! I am going to take it real easy this time!

Mar786 profile image
Mar786 in reply to Riri88

I know its soo frustrating as it is going through all the emotions that come with ivf!!

Iv been through Ivf before as-well (4yrs ago) and really had to use my own initiative as sometimes they can miss things.

Yes lets hope they sort things on monday.

Yes do take it easy i will be doing the same. Have a lovely weekend xx

Riri88 profile image
Riri88 in reply to Mar786

It is silly isn’t it. I definitely generally feel sometimes I am leading the consultant, not him leading me to the best options and outcome. I think they might under estimate how much ‘research’ we do ourselves these days 🤣

Mar786 profile image
Mar786 in reply to Riri88

Soooo true - honestly exactly how i feel !!

Ala00 profile image
Ala00 in reply to Mar786

Hi how did you get on? I'm looking for positive stories

Mar786 profile image
Mar786 in reply to Ala00

Hiii

I unfortunately had a miscarriage at around 6 weeks definitely think progesterone was part of it.. i had very strong lines and even my hcg numbers were high but i think due to having less progesterone from the start this caused me to have bleeds and then the pregnancy did not continue 🙁. I do however have another embryo to transfer which is a little lower grade but going to give it everything and jus pray for the best. Its good to always go with your instinct i would always advise that as the nursing team have made quite a few mistakes if i had not mentioned and even the progesterone had to keep chasing them to check it..

Ala00 profile image
Ala00 in reply to Mar786

Oh no I'm so sorry. When are you starting again?

Mar786 profile image
Mar786 in reply to Ala00

Yes did want to take a big break but then wanted to go straight back into it again so should be having a transfer in august. They will base the medication on my day 21 period from June.. but they have also added prednisone this time. I will also be doing endometrial scratch had the glue last time so will do that too.I did have a daughter 4 years ago i bled a-lot with her was always on the edge but it ended up being a sub choronic haemorrhage!!

IVF is full of soo much emotions honestly sometimes wounder were we get the strength from. So so expensive here to as im private.

Ala00 profile image
Ala00 in reply to Mar786

Oh no, so sorry, but sounds like you have a plan. It's awful isn't it. I just wish I was pregnant. I just had a 4bc transferred and feeling quite dejected. I really wish they didn't tell me the grading. This is my second transfer. I'm private too and it's dollar dollar. I have a baby too already (through IVF) and thought it would get easier. But it's just as hard. Sending you positive vibes

Mar786 profile image
Mar786 in reply to Ala00

Awwww i know!!!! Yes my child was also through ivf and I honestly thought would be easier too. Just don't feel like giving up really want a sibling for her but don't know if it will happen. I had a fresh cycle were there was only 1 embryo and then did another fresh which resulted in 3 embryos but had to freeze due to ohss and having 28 eggs collected!!!

Was such a shame only 3 made it to freeze had 2 transferred in march which resulted in my miscarriage..

I know the grading is really annoying but i have seen soo many ppl go on to having healthy baby's with this grade. My Embryo left to transfer is also this grade Frozen but day 6.

Sending you lots pf positivity too fingers crossed xx

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