Successful IVF/ICSI with high DNA frag?

[annadance]

Just wondering if anyone has had a successful pregnancy through IVF despite their partner having high DNA fragmentation?

Thanks xx

[Jm82]

Yes I did, my partners was 51% damaged which was terrible and we managed to reduce it down to 30% - still classed as bad but it worked and we now have a 6 month old. Good luck xx

[annadance in reply to Jm82]

Thank you that’s very good to hear and congratulations did you do ICSI? Xx

[Flora14 in reply to annadance]

That's amazing how did you get it down that much? Thanks

[LauraEW]

Yes my OH showed huge improvements after a supplement and diet plan, we are now 10 weeks pregnant after conceiving naturally having previously been told we had less than 10% chance! You can see our full story in my bio xx

[Ellie1005 in reply to LauraEW]

Hi Laura, thanks for sharing it would be really useful to know what supplements were suggested for your OH that worked, thank you! X ps congratulations on your pregnancy that’s amazing!

[Flora14 in reply to LauraEW]

Hi that's amazing please could you share what supplements and diet changes you had?

[waitingg]

Hi Anna, my husband had about 37% damaged and we changed clinic and did imsi after finding that out. We also found out I had immune issues and I had treatment for that so it might have been a bit of both but we had our little boy from that round. Dna was completely ignored by our first clinic - I don’t know why other than lack of resources maybe xx

[annadance in reply to waitingg]

Thank you that’s really helpful to know. I’ve not been tested for immune issues but perhaps that’s something to consider as well

Did you try icsi first? We’ve had 4 good quality blasts but zero luck implantation

X

[waitingg in reply to annadance]

Yes we had icsi first. My first round was cancelled as I had OHSS but we managed to freeze 5 blasts. We got through four of those over FETS and nothing. Then one more fresh round there and had a chemical. We left one remaining embryo frozen at the clinic and its still there. Changed clinic and did a fresh round and we had a little boy, and i'm now 9 weeks pregnant from a FET with the only other embryo from that successful cycle. This clinic are much tighter on progesterone and thyroid levels so I have extra meds for those too. It might be worth seeing what your clinic allows as I do wonder if the progesterone has something to do with it all too. Do message me if you want any more details. Lots of luck with your next steps xx

[ChloeDE]

We didn't do testing but my partner's sperm quality (morphology etc) was really bad. Our clinic recommended we use MACS. It's a magnetic procedure that helps pick out the best sperm. It might be worth looking into.It worked for us. We recently had twins.