DNA FRAGMENTAION TEST

[annadance]

Hello I was just wondering if someone could help me out - how do you work out the average result of a DNA fragmentation test?

I have both the low commet and the high commet results.

I can't speak to my doctor until next week so am just trying to figure it out in the mean time

many thanks

[soccerkt6]

Hi annadance

The tests results should show three scores - the average, low and high Comet scores. Do want to upload a pic of your results (don't include any of the personal info) so we can help?

[annadance in reply to soccerkt6]

Thanks so much for your response I don’t have a physical copy of the results as they were relayed over the phone but there was no mention of average. I wrote down these -

low commet was 48%

high commet - 16%

Both of which are in anormal range so presuming pretty bad 😢

[soccerkt6 in reply to annadance]

Ah, I see. Unfortunately, there's no way to work out the average based on the numbers they've given you. But you're right that they're outside of the normal range.

However, don't lose hope! The next steps after this are to start on a supplement (my husband's doc recommended Impryl for 3-6 months) and possibly get some further testing to see if a varicocele or infections are contributing to the problem. Hopefully your current doctor can guide you through this, but if not I would recommend self-referring to a urologist (loads of people on here rave about Dr Ramsay in London) to take foward next steps. Best of luck! xx

[annadance in reply to soccerkt6]

Thank you :)He’s actually been on impryl for a year so I don’t think it’s doing much sadly. But I’ve heard of Dr Ramsey so I think he will have to be the next step.

Thanks again xx

[soccerkt6 in reply to annadance]

No problem, lovely. I felt really defeated after my husband's test came back (his low Comet score was only 20%, so quite a bit worse than your husband's) but we've since found some infections that we've been able to treat. I promise it's not actually as bad as it seems right now and I have full confidence that Dr Ramsay will be able to lay out a game plan for you xx

[LBS08 in reply to annadance]

Hi, I am in the same position and we are undergoing IMSI. You should check it out xx

[annadance in reply to LBS08]

Hi thanks for your reply. Can I ask - did you try icsi first? We had 5 grade a blastocysts but so far 3 failed