IVF using own eggs, sperm dnor and PGD/PGS - Malaysia

[IVFmomtobe]

I am turning 40 next year...financially will be able to afford the process by then (single mom to be - please! )

anyone had an experience going to Metro IVF?

[Lizzielizzielizzie]

Pgd is different to pgs, make sure you’re clear about which you are having. Pgd usually only done if you’re at risk of passing on a genetic/chromosome condition.

[IVFmomtobe in reply to Lizzielizzielizzie]

thank you lizzie!

[Becca21]

I think if you're going for IVF the PGD part is obvious in most of the clinics as genetic evaluation of the embryo is important before FET. In short, PGD helps to identify a bad embryo. However, PGS is done only when there is a genetic issue is detected in PGD or there has been recurrent pregnancy loss that might have a link to genetic glitch. It's a clinical procedure to identify the glitch to be able to rectify that if possible. You can't really opt for PGS voluntarily unless there is really a problem. Also, the overall fertility gets deteriorated with age that's a known fact but what most people overlook is that there are ways to cope with it somewhat. I found a very interesting and informative video on "pregnancy and age" that talks about the possible cause of age-related infertility, the success rate of IVF at different ages for older women and effective fertility assistance for each of the well-known fertility issues that are quite predominant for older women. I can share the details if that helps!

[Lizzielizzielizzie in reply to Becca21]

That’s the wrong way round. PGS (preimplantation genetic screening) is the one you can choose to have that many clinics recommend for older women, although there is research that the UK Health agency quotes to say that having PGS reduces the chance of a live birth statistically. PGD (pre implantation genetic diagnosis) is the one where they are screening for a specific disorder that the embryo could have inherited. To be fair though, I think some US fertility centre sites do use the terms interchangeably, but they are technically very different processes and done for different purposes. Can I ask why you are interested in having pgs/pgd done? Do you have a known genetic disorder?

centerforhumanreprod.com/fe...

[Becca21 in reply to Lizzielizzielizzie]

I've written what I read on the internet. Not really a professional, but was just trying to help. I've got a link too so I guess the confusion can be best solved by Diane or some other expert.

Dear Diane if you happen to read this please do let me know which one is true. I'd love to be corrected if I have a wrong information.

Between Lizzie I found this here if you want to check

fertilitycenter.com/fertili...

[Lizzielizzielizzie in reply to Becca21]

Hi Becca your video says the same as what I’ve said, pgd is the diagnosis of abnormal embryos for a specific inherited disorder which is very likely to be passed on, pgs is the screening “just in case” embryos might be abnormal. I think we are saying the same thing really, it’s just a matter of which way round the acronyms go.

The reason I am certain about this is because I’m going through PGD due to my husband having a diagnosed chromosome translocation. It’s important to differentiate because PGD is proven to increase the chances of affected couples having an unaffected child whereas PGS is still debated. as I said above, there’s some research that suggests having PGS can reduce your chances of a live birth so if you are considering spending money on it then you need to look into it thoroughly. PGD is NHS funded in the UK for suitable couples but PGS is not.

Here is the HFEA information about PGS:

hfea.gov.uk/treatments/embr...

And about PGD-

hfea.gov.uk/treatments/embr...

[IVFmomtobe in reply to Lizzielizzielizzie]

Hi Lizzielizzielizzie !

I received valuable insights from both you and Becca21 . I will bring these information when I see the doctor at the earlier.

Thank you very very much dears!!

xoxo

[Becca21 in reply to Lizzielizzielizzie]

Hi Lizzie, I hope everything goes well with your PGD. Wish you luck! I'm still struggling with DE dilemmas. Just mentioned what I read as told earlier and not really any personal experience.

The PGD (as far as I could grasp from playing the video again) is the diagnosis part - to identify and understand the chromosomal translocation if any and get it eliminated. PGS is the technology in which a thorough screening targets aneuploidy. So, basically, it's like the two of them treat two different types of genetic glitch.

The part where you mentioned that PGD is to increase the chances that no offspring carry the genetic anomaly if any is exactly what I meant. It's a standard process to check any IVF embie for that. Can't agree more that difference between PGD and PGS is a little confusing.

[IVFmomtobe in reply to Becca21]

HI, Becca21 !

I will look into the url that you gave me today :0

[IVFmomtobe in reply to Lizzielizzielizzie]

40 is the magic number Lizzielizzielizzie . PGD/PGS will then be as per doctor's reference

Thank you very much

[IVFmomtobe in reply to Becca21]

Hello Becca21!

Appreciate your reply. I am at 40 by the time I do IVF so the PGD/PGS - would be as per doctor's reference - is really unavoidable.

Thank you very very much dear!

[Becca21 in reply to IVFmomtobe]

The first video by Dr Kotlik Julia on pregnancy and age that I referred is about the successful pregnancy at an older age. It doesn't really speak of PGS or PGD though. The links, however (both from me and Lizzie) talks about PGD and PGS though not very in-depth. I read you mentioned the age in your post and usually, people have this notion that age can be an inhibitor to being a mom really. So, just wanted to say - 40 isn't really much old for pregnancy with a little help from some good clinic. So, hopefully, that will somewhat boost your "40 is the magic number" belief. Do keep me updated, the positive news are really a dose of hope for me. Take care!

[IVFmomtobe in reply to Becca21]

I will update you the soonest. I have sent an inquiry to Metro IVF recently... they offered IVF with PGD for RM 29800/- so far they have been very responsive through email.

[Beebeestar]

Good luck!!