Lamotrigine and antihistamines

[Daffers123]

Have started Lamotrigine and developed itchy red Rash . Can I take Loratadine/certirizine to calm symptoms

[EpilepsyAction1 Partner Epilepsy Action]

A rash could be a reaction to the lamotrigine. It would be best to contact your doctor as soon as possible.

Hope it sorts quickly.

Regards

Cherry

Epilepsy Action Helpline Team

[Hidden]

Sounds like you are having an allergic response. Call your doctor immediately.

You do not want this to get worse. Allergic reactions can be deadly.

I could not take a migraine med because I developed a rash and swelling.

[KellyInTexas]

I hope you did seek medical attention. I developed a non necrolytic Stevens Johnson’s rash. My neurologist told me if I developed a rash at all, to go to the nearest A and E. Fortunately it is not the necrosis form- most are not.

I cannot take lamictal , and was switched to Dilantin, then vimpat, and ultimately topirimate.

[Deniseelk]

My daughter interestingly had a mild rash ( mainly on arms) when she upped Lamotrigine from 100 mg to 150mg ( in early days when she just started the med). It can often be a mild reaction to the body getting used to it. We went directly to her GP ( they took advice from Neurological dept) and she dropped down to 100mg for a further week then upped to 150mg with no problem. What I would say is seek medical advice but please don’t over worry as a mild skin reaction is quite common. Also, don’t change your medication levels until you have received medical advice.

[lgd333]

Sounds like an allergic reaction to the medication... Cetirizine is an antihistamine and helps with certain allergies, i.e. to food and more. I take it daily as I am allergic to wheat, dairy and protein amongst other things. Please speak to your doctor regarding a change in medication.

[lgd333]

I'm new on Lamotrigine (8 weeks now) and increasing dosage every 2 weeks. I'm also on blood thinners which cause Purpura also. During COVID-19 of course our GP practice is closed so trying to get advice from others. Today I increased to 100mg. and find a mild rash of purpura spots coming up more and more, but not sure if its the Lamotrigine or Aspirin?

Can anyone give some feedback?